Detailed information
Bioinformatically predicted
Overview
| Name | comGE | Type | Machinery gene |
| Locus tag | G8B46_RS00695 | Genome accession | NZ_CP049686 |
| Coordinates | 108310..108594 (+) | Length | 94 a.a. |
| NCBI ID | WP_011528162.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain TSPY637 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 103310..113594
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G8B46_RS00670 (G8B46_00670) | - | 105256..105621 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| G8B46_RS00675 (G8B46_00675) | comGA | 105714..106652 (+) | 939 | WP_002987773.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| G8B46_RS00680 (G8B46_00680) | comGB | 106588..107622 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| G8B46_RS00685 (G8B46_00685) | comGC | 107624..107950 (+) | 327 | WP_011528161.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| G8B46_RS00690 (G8B46_00690) | comGD | 107925..108353 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| G8B46_RS00695 (G8B46_00695) | comGE | 108310..108594 (+) | 285 | WP_011528162.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| G8B46_RS00700 (G8B46_00700) | comGF | 108587..109021 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| G8B46_RS00705 (G8B46_00705) | comGG | 109005..109331 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| G8B46_RS00710 (G8B46_00710) | comGH | 109429..110382 (+) | 954 | WP_021299429.1 | class I SAM-dependent methyltransferase | Machinery gene |
| G8B46_RS00715 (G8B46_00715) | - | 110441..111637 (+) | 1197 | WP_011528164.1 | acetate kinase | - |
| G8B46_RS00720 (G8B46_00720) | - | 111824..112132 (+) | 309 | WP_011528165.1 | hypothetical protein | - |
| G8B46_RS00725 (G8B46_00725) | proC | 112215..112985 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
Sequence
Protein
Download Length: 94 a.a. Molecular weight: 10686.65 Da Isoelectric Point: 8.9043
>NTDB_id=374067 G8B46_RS00695 WP_011528162.1 108310..108594(+) (comGE) [Streptococcus pyogenes strain TSPY637]
MGIIKKQVKAYIALESMIATGILFSIVILILSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE
MGIIKKQVKAYIALESMIATGILFSIVILILSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE
Nucleotide
Download Length: 285 bp
>NTDB_id=374067 G8B46_RS00695 WP_011528162.1 108310..108594(+) (comGE) [Streptococcus pyogenes strain TSPY637]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCATCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCATCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGE | Lactococcus lactis subsp. cremoris KW2 |
38.298 |
100 |
0.383 |
| comGE | Streptococcus mutans UA140 |
36.559 |
98.936 |
0.362 |
| comGE | Streptococcus mutans UA159 |
36.559 |
98.936 |
0.362 |