Detailed information NTG0037360

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SARLGA251_RS06495
• Genome accession: NC_017349
• Coordinates: 1319470..1322088 (+)
• Length: 872 a.a.
• NCBI ID: WP_000073345.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus LGA251
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1314470..1327088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SARLGA251_RS06470 (SARLGA251_12010)	-	1315352..1316218 (+)	867	WP_000190138.1	2-oxoacid:ferredoxin oxidoreductase subunit beta	-
SARLGA251_RS06475 (SARLGA251_12020)	-	1316312..1316605 (+)	294	WP_000655666.1	thiamine-binding protein	-
SARLGA251_RS06480 (SARLGA251_12030)	miaB	1316739..1318283 (+)	1545	WP_001001521.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
SARLGA251_RS06485 (SARLGA251_12040)	-	1318284..1318649 (+)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
SARLGA251_RS06490 (SARLGA251_12050)	thiW	1318676..1319167 (+)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
SARLGA251_RS06495 (SARLGA251_12060)	hexA	1319470..1322088 (+)	2619	WP_000073345.1	DNA mismatch repair protein MutS	Machinery gene
SARLGA251_RS06500 (SARLGA251_12070)	hexB	1322101..1324110 (+)	2010	WP_000516256.1	DNA mismatch repair endonuclease MutL	Machinery gene
SARLGA251_RS06505 (SARLGA251_12080)	-	1324116..1324658 (+)	543	WP_041201395.1	glycerol-3-phosphate responsive antiterminator	-
SARLGA251_RS06510 (SARLGA251_12090)	-	1325132..1325950 (+)	819	WP_001103747.1	MIP/aquaporin family protein	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99888.67 Da
• Isoelectric Point: 4.6493

>NTDB_id=37360 SARLGA251_RS06495 WP_000073345.1 1319470..1322088(+) (hexA) [Staphylococcus aureus subsp. aureus LGA251]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDHLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIVRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQDTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNMQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERIQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENSSLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=37360 SARLGA251_RS06495 WP_000073345.1 1319470..1322088(+) (hexA) [Staphylococcus aureus subsp. aureus LGA251]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAGGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGTGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAACATTTCCGATCATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCATCTGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCCAAAAAAGGAACGCTACTTTGGCTGATGGACGAAACGAAAACACCAATGGGAGCACGTCGATTAAAACAATGGATAG
TTAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAAATACCGAACATTAAAGCATTACTAAATTCTATGAATCAGGATA
CTCTTGTACAAGTTAATCAACTAGAACCACTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGTGGACTATTCAAAGTTGGTTTTAATATGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAACTACAAGCCAAAGAAAGACAACGTACAGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCGGAACGATTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
TATTGAATTAGAATATCAATTATTTGTTCAGTTACGTGAAGAAGTTAAAAAATATACTGAACGTATACAACAACAAGCTA
AAATTATTTCAGAGTTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTATACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCAGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAATGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACGTATATGAGAC
AAGTTGCCATAATTAGCATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCTGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCACATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATTCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTCAAGCTTAAGTGTTGAAGAAACAACTGATACGTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (125-237)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (5-115)

• MutS family domain IV (MutS_IV) (412-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.341	100	0.458