Detailed information NTG0037356

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SARLGA251_RS06285
• Genome accession: NC_017349
• Coordinates: 1272517..1273290 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus subsp. aureus LGA251
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1267517..1278290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SARLGA251_RS06265 (SARLGA251_11620)	trmFO	1267860..1269167 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SARLGA251_RS06270 (SARLGA251_11630)	xerC	1269585..1270481 (+)	897	WP_001015609.1	tyrosine recombinase XerC	-
SARLGA251_RS06275 (SARLGA251_11640)	hslV	1270478..1271023 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
SARLGA251_RS06280 (SARLGA251_11650)	hslU	1271089..1272492 (+)	1404	WP_000379045.1	ATP-dependent protease ATPase subunit HslU	-
SARLGA251_RS06285 (SARLGA251_11660)	codY	1272517..1273290 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SARLGA251_RS06290	-	1273341..1273433 (+)	93	WP_031788481.1	hypothetical protein	-
SARLGA251_RS06295 (SARLGA251_11670)	rpsB	1273632..1274399 (+)	768	WP_000268480.1	30S ribosomal protein S2	-
SARLGA251_RS06300	-	1274433..1274546 (+)	114	WP_001789890.1	hypothetical protein	-
SARLGA251_RS06305 (SARLGA251_11680)	tsf	1274581..1275462 (+)	882	WP_000201387.1	translation elongation factor Ts	-
SARLGA251_RS06310 (SARLGA251_11690)	pyrH	1275599..1276321 (+)	723	WP_000057330.1	UMP kinase	-
SARLGA251_RS06315 (SARLGA251_11700)	frr	1276340..1276894 (+)	555	WP_001280006.1	ribosome recycling factor	-
SARLGA251_RS06320 (SARLGA251_11710)	-	1277267..1278037 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=37356 SARLGA251_RS06285 WP_000055337.1 1272517..1273290(+) (codY) [Staphylococcus aureus subsp. aureus LGA251]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=37356 SARLGA251_RS06285 WP_000055337.1 1272517..1273290(+) (codY) [Staphylococcus aureus subsp. aureus LGA251]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428