Detailed information NTG0373359

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: E3226_RS08190
• Genome accession: NZ_CP041713
• Coordinates: 1736869..1739631 (-)
• Length: 920 a.a.
• NCBI ID: WP_187356849.1
• Uniprot ID: -
• Organism: Legionella geestiana strain HL-0438-4026
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1731869..1744631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3226_RS08170 (E3226_007885)	-	1733253..1734656 (-)	1404	WP_028385929.1	APC family permease	-
E3226_RS08175 (E3226_007890)	-	1734733..1735056 (-)	324	WP_028385928.1	BolA family protein	-
E3226_RS08180 (E3226_007895)	comP	1735173..1735616 (+)	444	WP_028385927.1	pilin	Machinery gene
E3226_RS08185 (E3226_007900)	-	1735626..1736858 (-)	1233	WP_135842655.1	6-phosphofructokinase	-
E3226_RS08190 (E3226_007905)	letS	1736869..1739631 (-)	2763	WP_187356849.1	two-component system sensor histidine kinase LetS	Regulator
E3226_RS08195 (E3226_007910)	gltX	1739725..1741134 (+)	1410	WP_135842656.1	glutamate--tRNA ligase	-
E3226_RS08200 (E3226_007915)	-	1741207..1741428 (+)	222	WP_028385924.1	hypothetical protein	-
E3226_RS12485	-	1741522..1741677 (+)	156	WP_155832455.1	hypothetical protein	-

Sequence

Protein

• Length: 920 a.a.
• Molecular weight: 102622.32 Da
• Isoelectric Point: 6.7015

>NTDB_id=373359 E3226_RS08190 WP_187356849.1 1736869..1739631(-) (letS) [Legionella geestiana strain HL-0438-4026]
MGIKYQLRVTTLIPVLLVALLFAVFYNGQYGHDLKQHMSRLGEAYIRQLLPAAQFAMLQKDARTLQGLINASSINPEIKT
IAFYNREGELLAYRGGKHSLVKPFSPPPFTGDYIESRHIDTNTIHFVAPVTLPQYNLYAPRPAVSHRVPLAWQPDDVLGW
LSIDIDTQSTLIKRYQMYMVTTFITLLGLLIGLSVHFFFARRIYLPITRLRRSMSQILRNEFETPVRTTSHGDLGTIERG
CAHLQRQYLDAVEDLNQHIETATADLQQSLELLEEKNVELLLEKKKAEEKSRQKSEFIANMSHEIRTPMNGVIGFTNVLL
EGKLDPLQMDYVKTIKSSAHDLLTIINDILDYSKMDAGKLHLDCIPLDIRACIDEVLTLSAPNAHRKGLDLIPITDVSVP
HMVLGDPLRIKQIIRNLVGNAVKFTDRGFVLVRTHIQAETQRDYTLCLSVTDTGIGIAPEDQTRLFNAFNQADTTIIRRF
GGTGLGLVICKKLTEEMQGKISLESTPHKGSTFSVTLRLEKLTAYEVEKNQSRRFAHLSALCFDENPLHLEALCNGLGYW
GVQCTPTGNLKELEEMMRSSQSFDIAFVHVNQGCERQIAPILKIRNLPAVAVAKQFIPDHDTLGAAAFLFKPISIQKLMD
TLEMLQNTATPSLEPEQARLRTRLQSVCPDVLLAEDNAVNRLLMNSLLAGHARVVAVSDGEEAVALCDTKRFHAILLDLQ
MPRMGGLEAASRIRHASLLNRDTPIAVISANSTDLHAEQLQKAGVSLCLQKPVDEKELFEYLLDALHQAQNAVIDWPVCL
QKASNNEALAREFMARFVEDLVKERPEFVRFFATNQVKALENAAHRLHGACCFCGVPKLMEQVVLLETSARGASDCASLE
DIFRAFLESLDAVAAAWANGDFAASAASSLPSKAIESSHP

Nucleotide

• Length: 2763 bp

>NTDB_id=373359 E3226_RS08190 WP_187356849.1 1736869..1739631(-) (letS) [Legionella geestiana strain HL-0438-4026]
ATGGGAATCAAATACCAGCTGCGTGTTACCACCCTCATTCCAGTACTGCTGGTTGCCCTTCTTTTTGCGGTATTTTATAA
CGGCCAGTACGGGCACGATCTTAAACAGCACATGTCACGCCTTGGGGAAGCTTACATTCGTCAGCTTCTGCCAGCCGCCC
AGTTTGCCATGCTGCAAAAAGACGCCCGCACGCTTCAGGGACTTATCAACGCATCTTCCATCAACCCTGAAATCAAAACC
ATCGCATTTTATAACCGTGAGGGCGAACTGCTCGCCTATCGCGGCGGCAAGCATTCGCTGGTCAAACCCTTCTCACCGCC
CCCTTTTACCGGCGACTATATCGAAAGCCGTCATATCGACACCAACACCATCCACTTTGTGGCTCCCGTGACGCTGCCAC
AATATAACCTCTACGCCCCACGGCCTGCCGTATCGCACAGAGTTCCCCTCGCCTGGCAGCCTGATGACGTGCTTGGCTGG
CTCTCTATCGATATCGACACCCAGTCAACCCTCATCAAGCGCTATCAGATGTACATGGTGACCACGTTCATCACGCTGCT
TGGCCTGCTCATTGGACTCAGCGTGCATTTTTTCTTCGCACGCCGCATTTATCTGCCAATTACCCGCCTGCGACGCAGCA
TGAGCCAGATTCTGCGCAACGAGTTTGAAACCCCGGTGCGCACGACCAGTCACGGGGACCTTGGTACCATCGAGCGCGGC
TGTGCGCATCTGCAGCGACAGTATCTCGATGCCGTTGAAGATTTAAACCAGCACATCGAAACCGCCACCGCCGACCTGCA
GCAAAGCCTTGAGCTTTTAGAAGAAAAAAACGTTGAACTGCTGCTCGAAAAGAAAAAAGCGGAGGAAAAAAGCCGCCAGA
AATCGGAATTCATTGCCAATATGAGCCATGAAATCCGTACCCCCATGAACGGCGTTATCGGCTTTACCAATGTGCTGCTC
GAGGGCAAACTCGACCCCCTGCAGATGGATTATGTGAAAACCATTAAATCTTCGGCGCATGATTTACTGACTATCATCAA
CGACATCCTGGATTATTCCAAAATGGATGCGGGCAAACTGCACCTTGACTGTATTCCCCTCGATATTCGCGCCTGTATCG
ATGAGGTCCTGACGCTTTCTGCACCTAACGCGCACCGCAAGGGACTTGACCTTATCCCGATTACCGATGTTTCGGTGCCG
CACATGGTGCTTGGCGACCCGCTGCGCATCAAGCAGATTATCCGAAACCTCGTTGGCAACGCGGTCAAATTTACCGACAG
AGGCTTCGTGCTGGTGCGTACCCATATTCAGGCGGAAACCCAGAGAGATTACACCCTCTGCCTCTCAGTGACTGACACCG
GCATTGGCATTGCACCAGAAGATCAGACCCGGCTCTTCAATGCGTTTAACCAGGCCGACACCACTATTATCCGCCGTTTT
GGCGGTACCGGTCTTGGACTTGTTATCTGCAAAAAACTGACGGAAGAGATGCAGGGTAAAATCAGCCTCGAGAGTACGCC
ACACAAAGGCTCTACCTTTTCAGTCACCCTGCGGCTTGAAAAACTCACGGCCTACGAAGTCGAAAAAAATCAGAGCCGCC
GTTTCGCACACCTTTCCGCACTCTGTTTTGATGAAAATCCACTGCATCTTGAAGCACTTTGCAATGGCCTTGGATACTGG
GGCGTCCAGTGTACTCCGACCGGTAACCTCAAAGAACTGGAAGAGATGATGCGCTCGAGTCAAAGCTTTGATATCGCATT
TGTGCACGTCAACCAGGGCTGCGAGCGCCAGATAGCTCCCATTCTTAAAATTCGCAACCTCCCGGCTGTCGCCGTTGCCA
AACAATTCATACCTGATCATGATACTCTGGGTGCGGCCGCTTTCCTGTTTAAGCCCATCAGCATTCAAAAACTCATGGAT
ACCCTGGAGATGCTGCAGAATACGGCAACCCCGTCTCTCGAGCCCGAGCAGGCGCGTCTGCGTACACGTTTACAATCAGT
TTGTCCCGATGTGCTGCTTGCAGAAGACAATGCCGTTAACCGGCTCTTGATGAATTCACTGCTGGCCGGACACGCACGGG
TGGTCGCGGTATCGGATGGGGAAGAAGCCGTGGCGCTGTGCGATACCAAGCGTTTCCATGCGATTCTTCTTGATTTACAG
ATGCCGCGCATGGGGGGACTCGAGGCCGCTTCGCGCATCCGTCATGCCTCGCTGTTAAACCGCGATACTCCCATCGCGGT
TATCAGCGCGAACAGTACTGACCTGCATGCCGAACAACTGCAAAAAGCCGGGGTGAGCCTGTGCCTGCAAAAGCCTGTGG
ATGAGAAAGAGCTGTTTGAGTACCTGCTTGATGCCCTGCACCAGGCGCAAAATGCCGTCATTGACTGGCCGGTCTGTCTG
CAAAAAGCATCTAATAATGAGGCACTTGCCCGCGAATTTATGGCGCGCTTTGTAGAGGATTTGGTAAAAGAGCGTCCTGA
ATTCGTCCGTTTTTTTGCCACTAATCAAGTCAAAGCGCTGGAAAATGCCGCGCACAGGCTCCATGGAGCCTGCTGCTTTT
GCGGGGTGCCAAAGCTGATGGAGCAGGTGGTGCTCCTTGAAACCAGCGCACGCGGCGCCAGTGACTGCGCATCGCTAGAG
GATATTTTCCGTGCATTCCTCGAAAGCCTTGATGCAGTAGCTGCTGCGTGGGCAAACGGCGATTTTGCTGCCAGCGCAGC
CTCATCCCTGCCGTCAAAAGCCATAGAATCGTCTCACCCATGA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (294-358)

• Response regulator receiver domain (Response_reg) (671-781)

• Hpt domain (Hpt) (813-892)

• Single cache domain 4 (sCache_4) (32-176)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (405-520)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	62.639	98.043	0.614