Detailed information NTG0371932

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ST64987_RS07760
• Genome accession: NZ_CP049053
• Coordinates: 1474675..1475460 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain ST64987
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1469675..1480460

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS07725 (ST64987_1469)	gatC	1469740..1470042 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
ST64987_RS07730	-	1470182..1470436 (-)	255	WP_024010053.1	glycosyl transferase	-
ST64987_RS07735 (ST64987_1470)	-	1470449..1470658 (-)	210	WP_080998437.1	glycosyltransferase	-
ST64987_RS07740 (ST64987_1471)	-	1470974..1472415 (-)	1442	Protein_1438	6-phospho-beta-glucosidase	-
ST64987_RS07745 (ST64987_1472)	msrA	1472568..1473077 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
ST64987_RS07750 (ST64987_1473)	-	1473089..1473937 (-)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
ST64987_RS07755 (ST64987_1474)	-	1474061..1474612 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
ST64987_RS07760 (ST64987_1475)	codY	1474675..1475460 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ST64987_RS07765 (ST64987_1476)	-	1475720..1476934 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
ST64987_RS07770 (ST64987_1477)	-	1477289..1477741 (+)	453	WP_002946987.1	universal stress protein	-
ST64987_RS07775	-	1477921..1478492 (+)	572	Protein_1445	IS30 family transposase	-
ST64987_RS07780 (ST64987_1478)	-	1478564..1478737 (-)	174	WP_167401590.1	hypothetical protein	-
ST64987_RS07785 (ST64987_1479)	-	1478798..1479172 (-)	375	WP_011681547.1	membrane protein	-
ST64987_RS07790 (ST64987_1480)	pflA	1479384..1480184 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=371932 ST64987_RS07760 WP_002951720.1 1474675..1475460(-) (codY) [Streptococcus thermophilus strain ST64987]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=371932 ST64987_RS07760 WP_002951720.1 1474675..1475460(-) (codY) [Streptococcus thermophilus strain ST64987]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACATTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502