Detailed information NTG0367226

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FDP16_RS07725
• Genome accession: NZ_CP040798
• Coordinates: 1551369..1552229 (-)
• Length: 286 a.a.
• NCBI ID: WP_176799211.1
• Uniprot ID: A0A7H8V1Y7
• Organism: Streptococcus sanguinis strain CGMH058
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1546369..1557229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDP16_RS07700 (FDP16_08010)	-	1546383..1547111 (-)	729	WP_176799795.1	hypothetical protein	-
FDP16_RS07705 (FDP16_08015)	-	1547257..1547814 (-)	558	WP_176799207.1	hypothetical protein	-
FDP16_RS07710 (FDP16_08020)	-	1547950..1549845 (-)	1896	WP_176799208.1	ABC-F family ATP-binding cassette domain-containing protein	-
FDP16_RS07715 (FDP16_08030)	-	1550098..1550463 (-)	366	WP_176799209.1	hypothetical protein	-
FDP16_RS07720 (FDP16_08035)	-	1550468..1551187 (-)	720	WP_176799210.1	matrixin family metalloprotease	-
FDP16_RS07725 (FDP16_08040)	endA	1551369..1552229 (-)	861	WP_176799211.1	DNA/RNA non-specific endonuclease	Machinery gene
FDP16_RS07730 (FDP16_08045)	-	1552288..1552470 (-)	183	WP_002917490.1	DNA-directed RNA polymerase subunit beta	-
FDP16_RS07735 (FDP16_08050)	murA	1552463..1553743 (-)	1281	WP_176799212.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FDP16_RS07740 (FDP16_08055)	-	1553811..1554041 (-)	231	WP_002897901.1	DUF1146 family protein	-
FDP16_RS07745 (FDP16_08060)	-	1554217..1554639 (-)	423	WP_176799213.1	F0F1 ATP synthase subunit epsilon	-
FDP16_RS07750 (FDP16_08065)	atpD	1554647..1556053 (-)	1407	WP_176799214.1	F0F1 ATP synthase subunit beta	-
FDP16_RS07755 (FDP16_08070)	-	1556092..1556973 (-)	882	WP_002895995.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31314.00 Da
• Isoelectric Point: 10.0684

>NTDB_id=367226 FDP16_RS07725 WP_176799211.1 1551369..1552229(-) (endA) [Streptococcus sanguinis strain CGMH058]
MKRKTSQKRNSKRLQGWAGLTLALILALAGYFWGQDGQQPLQSPNSEIRVGQVQDQGTPSRELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNKTDLDAGISSKPYADNKTKLVQGQTLPTVANAFLSKSTRQYKKREETGNANTSWVPAGWHQLKNLPG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANETDSTGQNYYETKIRKALDKNKRVRYRVTLIYATET
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIRLDYNSGRVSLDTGS

Nucleotide

• Length: 861 bp

>NTDB_id=367226 FDP16_RS07725 WP_176799211.1 1551369..1552229(-) (endA) [Streptococcus sanguinis strain CGMH058]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGGCTGCAAGGCTGGGCTGGGCTGACTCTAGCCTTGATTTTAGC
TCTGGCTGGCTATTTCTGGGGACAGGATGGTCAGCAACCACTTCAGAGTCCAAATTCAGAAATCAGGGTTGGACAAGTCC
AAGATCAGGGCACCCCTAGTCGGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAGCTCAAAGGCAGCATT
GAATGGAACGGAGCTGGTGCCTTTATCGTGAATGGGAATAAGACGGACTTGGATGCGGGGATTTCTAGTAAACCCTATGC
TGACAATAAGACCAAGCTTGTACAAGGGCAAACCCTTCCGACAGTGGCGAATGCCTTTTTATCCAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTGGAAATGCCAACACCTCATGGGTACCGGCAGGCTGGCATCAACTCAAGAACCTCCCTGGT
GAGTACAATCATGCTGTGGACCGAGGACATCTCTTGGCCTATTCGCTGATCGGTGGTTTGAAGGGCTTTGATGCCTCTAC
CAGCAATCCTGCCAATATCGCCGTGCAGACGGCTTGGTCCAACCAAGCCAATGAAACGGATTCGACAGGGCAGAATTACT
ATGAGACAAAGATCCGGAAGGCTTTGGATAAGAACAAGCGGGTGCGCTACCGGGTAACCTTGATTTATGCCACGGAGACA
GATTTAGTGCCGGTTGGGTCACATTTAGAGGCCAAGTCCAGCGATGGCAGTCTGGAATTTAATGTCTTTATCCCGAATGT
GCAAAAAGGGATTCGCCTGGACTATAATAGTGGCAGGGTCAGTCTGGACACGGGTTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (88-256)

3D structure

• AlphaFold DB: A0A7H8V1Y7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	74.554	78.322	0.584
endA	Streptococcus pneumoniae D39	74.554	78.322	0.584
endA	Streptococcus pneumoniae R6	74.554	78.322	0.584
endA	Streptococcus pneumoniae TIGR4	74.554	78.322	0.584