Detailed information NTG0366874

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: FG051_RS11410
• Genome accession: NZ_CP040736
• Coordinates: 2290375..2292531 (-)
• Length: 718 a.a.
• NCBI ID: WP_057812714.1
• Uniprot ID: A0A5B7T1M8
• Organism: Companilactobacillus futsaii strain Y97
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2285375..2297531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FG051_RS11375 (FG051_11375)	-	2286379..2286537 (+)	159	WP_149029869.1	bacteriocin	-
FG051_RS11380 (FG051_11380)	-	2286568..2286741 (+)	174	WP_149029870.1	bacteriocin	-
FG051_RS11385 (FG051_11385)	-	2287158..2287484 (-)	327	WP_057812724.1	hypothetical protein	-
FG051_RS11390 (FG051_11390)	-	2287770..2288090 (-)	321	WP_057812722.1	bacteriocin immunity protein	-
FG051_RS11395 (FG051_11395)	-	2288454..2288654 (-)	201	WP_229239888.1	leucocin A/sakacin P family class II bacteriocin	-
FG051_RS11400 (FG051_11400)	-	2288707..2288964 (-)	258	WP_057812718.1	helix-turn-helix domain-containing protein	-
FG051_RS11405 (FG051_11405)	-	2288984..2290363 (-)	1380	WP_057812716.1	bacteriocin secretion accessory protein	-
FG051_RS11410 (FG051_11410)	comA	2290375..2292531 (-)	2157	WP_057812714.1	peptide cleavage/export ABC transporter	Regulator
FG051_RS11415 (FG051_11415)	-	2292683..2293603 (+)	921	WP_149029810.1	IS30 family transposase	-
FG051_RS11420 (FG051_11420)	-	2293802..2293936 (+)	135	WP_149029871.1	EntF family bacteriocin induction factor	-
FG051_RS11425 (FG051_11425)	-	2293972..2295285 (+)	1314	WP_057812840.1	GHKL domain-containing protein	-
FG051_RS11430 (FG051_11430)	-	2295282..2296028 (+)	747	WP_057812837.1	response regulator	-
FG051_RS11435 (FG051_11435)	-	2296060..2296353 (+)	294	WP_057812834.1	hypothetical protein	-
FG051_RS11440 (FG051_11440)	-	2296556..2296906 (+)	351	WP_057812832.1	bacteriocin immunity protein	-
FG051_RS11445 (FG051_11445)	-	2296917..2297252 (+)	336	WP_057812830.1	hypothetical protein	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 81013.67 Da
• Isoelectric Point: 9.4900

>NTDB_id=366874 FG051_RS11410 WP_057812714.1 2290375..2292531(-) (comA) [Companilactobacillus futsaii strain Y97]
MRRKDIYTSQVDESDCGVAALAMILKNYGSNYSIARLRNFAKTNREGTTALGLVKTAQKLNFETQAIQTDMTLFKEKDIP
YPFIAHVVKNKVLEHYYVILGCTKKYILVADPDPTVKVTKMSYEKFSSEWKGVALFFAPNSEYKPEKIDKKGSLFSFVPV
LFKQKRLVVNIILAALLITIISILGSYFLQTVIDTYIPNNMSNTLAIISLGLIILYVFQSMFTYSRDFLLSILGQRLSID
IILGYIRHIFELPMDFFATRKTGEIVSRFNDANKIIDALASTIISIFLDLGIVIIMGTVLAIQNGTLFLITLISLPVYVV
IIWIFSKPFEKLNQKEMESGSVLNSSIIEDIHGIETIKALTSEDQRYSKIDSEFVDYLKKSLSYIKADTLQQALKLFIQL
VLSVVVLWVGALMVTKNRLSVGQLMTYNALLAYFVNPLQNIINLQPKLQSAKVANNRLNEVYLVDSEFKERRTVKKSAQL
VGDIKLTNVDFSYGYGENVLNDITLDIHSGEKVTIVGMRGSGKSTLVKLLVDFFKPIKGKVSINEHDVQNIDKYVLRRFI
NYIPQTPYIFSGSILKNLTLGNRENISNEDILEACKIAQIDEDIEKMPLQFETVLDENGNTLSGGQKQRITIARALLSPA
KVLIFDESTSGLDSITENNIMNNLMKIKGLTVIFIAHRLSIAKKTDNIVVLNKGRIVEKGTHQELVNKKGYYFDLLNN

Nucleotide

• Length: 2157 bp

>NTDB_id=366874 FG051_RS11410 WP_057812714.1 2290375..2292531(-) (comA) [Companilactobacillus futsaii strain Y97]
ATGAGAAGAAAGGACATTTATACATCCCAAGTTGATGAAAGTGACTGTGGAGTGGCTGCTTTGGCTATGATTCTAAAGAA
TTATGGGTCTAATTATTCTATAGCAAGGTTGCGTAACTTTGCAAAAACTAACAGAGAAGGCACCACGGCCCTAGGTTTGG
TAAAAACGGCTCAAAAGTTAAATTTTGAGACCCAAGCTATTCAGACAGATATGACCCTTTTTAAAGAAAAAGATATTCCA
TATCCATTTATTGCACATGTGGTAAAGAATAAAGTATTGGAACATTACTATGTGATTTTAGGATGTACAAAAAAATATAT
TCTTGTGGCTGATCCTGATCCAACAGTTAAAGTAACTAAAATGAGTTACGAAAAATTTTCTTCTGAATGGAAGGGTGTGG
CTCTATTTTTTGCACCTAATTCAGAGTATAAACCTGAAAAAATTGATAAGAAAGGGTCTCTTTTTTCATTTGTGCCTGTT
CTTTTTAAACAAAAAAGATTAGTAGTTAATATTATTTTGGCAGCATTGTTGATAACTATTATTAGTATTTTAGGATCTTA
TTTCTTACAAACAGTTATCGATACATATATTCCTAACAATATGAGCAATACTTTAGCAATCATTTCTTTAGGATTGATTA
TTCTTTATGTTTTCCAATCTATGTTTACCTATTCTAGAGATTTCTTATTATCTATTTTGGGTCAAAGACTTTCTATTGAT
ATTATTTTGGGATATATTCGTCATATTTTTGAATTGCCTATGGATTTCTTTGCTACTAGAAAAACAGGAGAGATTGTTTC
TAGATTTAATGATGCCAATAAGATTATTGATGCCTTAGCAAGTACAATAATTTCTATATTTTTGGATTTAGGAATTGTAA
TTATAATGGGAACTGTTTTGGCAATTCAAAATGGAACTTTATTTTTAATAACACTAATTTCCTTGCCTGTTTATGTAGTA
ATAATTTGGATATTTTCTAAACCATTCGAAAAATTAAATCAAAAAGAAATGGAGAGTGGATCAGTTTTAAACTCTTCAAT
TATTGAAGATATTCATGGAATTGAAACAATCAAAGCATTGACTAGTGAAGACCAGCGATATTCTAAAATTGATAGTGAGT
TTGTGGATTATTTAAAGAAAAGCTTGAGTTATATAAAAGCCGACACATTACAACAAGCGTTAAAGTTATTTATTCAATTA
GTTTTAAGTGTAGTTGTGTTATGGGTCGGAGCTCTTATGGTGACTAAGAATCGTTTGTCTGTTGGTCAATTAATGACTTA
TAATGCTTTGCTTGCATATTTTGTTAATCCTTTACAGAATATTATTAATTTACAGCCCAAATTACAATCAGCAAAGGTTG
CTAATAACAGGTTGAATGAAGTCTACTTAGTTGATTCCGAATTCAAAGAAAGACGCACGGTTAAAAAGTCTGCCCAATTA
GTCGGAGATATTAAATTAACAAACGTTGATTTTAGTTACGGATATGGAGAAAATGTTTTGAATGATATTACTTTAGATAT
TCATTCTGGTGAAAAGGTTACTATTGTGGGAATGAGGGGGTCTGGAAAATCAACATTGGTTAAGCTATTAGTAGATTTTT
TTAAACCTATTAAAGGAAAGGTTTCTATTAATGAACATGATGTTCAGAATATTGATAAATATGTTTTGAGACGATTTATT
AACTATATCCCTCAAACACCTTACATTTTTTCAGGAAGTATTCTAAAGAATCTAACTTTGGGAAATAGAGAGAATATCAG
TAATGAGGATATTTTAGAAGCATGTAAAATTGCCCAAATAGATGAAGATATAGAGAAAATGCCGTTGCAGTTTGAGACTG
TTTTGGACGAAAACGGTAATACTTTATCTGGTGGACAAAAACAAAGAATCACCATTGCTAGGGCATTACTGTCTCCAGCC
AAAGTTTTAATATTTGATGAATCTACTAGTGGGTTAGATTCTATAACTGAAAATAATATTATGAACAATTTGATGAAAAT
TAAAGGATTGACGGTCATCTTTATTGCTCATAGACTATCTATCGCAAAAAAGACAGATAATATTGTAGTGTTGAATAAAG
GAAGAATTGTAGAAAAGGGAACACATCAAGAGTTAGTAAATAAAAAAGGTTATTACTTTGATCTTTTGAATAATTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-141)

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

3D structure

• AlphaFold DB: A0A5B7T1M8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	57.303	99.164	0.568
comA	Streptococcus mitis SK321	56.923	99.582	0.567
comA	Streptococcus pneumoniae D39	56.503	99.582	0.563
comA	Streptococcus pneumoniae Rx1	56.503	99.582	0.563
comA	Streptococcus pneumoniae R6	56.503	99.582	0.563
comA	Streptococcus pneumoniae TIGR4	56.503	99.582	0.563
comA	Streptococcus gordonii str. Challis substr. CH1	56.285	99.721	0.561
comA/nlmT	Streptococcus mutans UA159	55.447	99.721	0.553