Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E3S74_RS05980 Genome accession   NZ_CP047851
Coordinates   1248283..1249056 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain UP_338     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1243283..1254056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S74_RS05960 (E3S74_05960) trmFO 1243626..1244933 (+) 1308 WP_000195263.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  E3S74_RS05965 (E3S74_05965) xerC 1245351..1246247 (+) 897 WP_001015609.1 tyrosine recombinase XerC -
  E3S74_RS05970 (E3S74_05970) hslV 1246244..1246789 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E3S74_RS05975 (E3S74_05975) hslU 1246855..1248258 (+) 1404 WP_000379051.1 ATP-dependent protease ATPase subunit HslU -
  E3S74_RS05980 (E3S74_05980) codY 1248283..1249056 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E3S74_RS05985 (E3S74_05985) - 1249107..1249199 (+) 93 WP_031788481.1 hypothetical protein -
  E3S74_RS05990 (E3S74_05990) rpsB 1249398..1250165 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  E3S74_RS05995 (E3S74_05995) - 1250199..1250312 (+) 114 WP_001791405.1 hypothetical protein -
  E3S74_RS06000 (E3S74_06000) tsf 1250347..1251228 (+) 882 WP_000201387.1 translation elongation factor Ts -
  E3S74_RS06005 (E3S74_06005) pyrH 1251365..1252087 (+) 723 WP_000057330.1 UMP kinase -
  E3S74_RS06010 (E3S74_06010) frr 1252106..1252660 (+) 555 WP_094433807.1 ribosome recycling factor -
  E3S74_RS06015 (E3S74_06015) - 1253033..1253803 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=365409 E3S74_RS05980 WP_000055337.1 1248283..1249056(+) (codY) [Staphylococcus aureus strain UP_338]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=365409 E3S74_RS05980 WP_000055337.1 1248283..1249056(+) (codY) [Staphylococcus aureus strain UP_338]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428