Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EUC38_RS22860 Genome accession   NZ_CP040340
Coordinates   4558203..4558982 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus cereus strain DLOU-Tangshan     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 4532909..4594668 4558203..4558982 within 0


Gene organization within MGE regions


Location: 4532909..4594668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EUC38_RS22750 - 4533480..4534379 (-) 900 WP_000868217.1 polysaccharide deacetylase family protein -
  EUC38_RS22755 pnp 4534531..4536669 (-) 2139 WP_000076737.1 polyribonucleotide nucleotidyltransferase -
  EUC38_RS22760 rpsO 4536830..4537099 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  EUC38_RS22765 ribF 4537200..4538171 (-) 972 WP_000766706.1 bifunctional riboflavin kinase/FAD synthetase -
  EUC38_RS22770 truB 4538215..4539138 (-) 924 WP_000399352.1 tRNA pseudouridine(55) synthase TruB -
  EUC38_RS22775 rbfA 4539225..4539581 (-) 357 WP_000776437.1 30S ribosome-binding factor RbfA -
  EUC38_RS22780 - 4539597..4539878 (-) 282 WP_000582363.1 DUF503 family protein -
  EUC38_RS22785 infB 4539875..4541935 (-) 2061 WP_000036343.1 translation initiation factor IF-2 -
  EUC38_RS22790 - 4541940..4542251 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  EUC38_RS22795 - 4542252..4542524 (-) 273 WP_000071127.1 YlxR family protein -
  EUC38_RS22800 nusA 4542536..4543642 (-) 1107 WP_000102604.1 transcription termination factor NusA -
  EUC38_RS22805 rimP 4543660..4544130 (-) 471 WP_000359096.1 ribosome maturation factor RimP -
  EUC38_RS22810 - 4544467..4548768 (-) 4302 WP_000060005.1 PolC-type DNA polymerase III -
  EUC38_RS22815 - 4548893..4550593 (-) 1701 WP_000814299.1 proline--tRNA ligase -
  EUC38_RS22820 rseP 4550703..4551959 (-) 1257 WP_001090244.1 RIP metalloprotease RseP -
  EUC38_RS22825 dxr 4551977..4553119 (-) 1143 WP_000790373.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  EUC38_RS22830 cdsA 4553143..4553934 (-) 792 WP_000813592.1 phosphatidate cytidylyltransferase -
  EUC38_RS22835 uppS 4553952..4554728 (-) 777 WP_000971296.1 isoprenyl transferase -
  EUC38_RS22840 frr 4554814..4555371 (-) 558 WP_000531501.1 ribosome recycling factor -
  EUC38_RS22845 pyrH 4555374..4556096 (-) 723 WP_000042668.1 UMP kinase -
  EUC38_RS22850 tsf 4556163..4557050 (-) 888 WP_001018578.1 translation elongation factor Ts -
  EUC38_RS22855 rpsB 4557154..4557855 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  EUC38_RS22860 codY 4558203..4558982 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EUC38_RS22865 hslU 4559060..4560451 (-) 1392 WP_000550078.1 ATP-dependent protease ATPase subunit HslU -
  EUC38_RS22870 hslV 4560474..4561016 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  EUC38_RS22875 xerC 4561059..4561958 (-) 900 WP_001101243.1 tyrosine recombinase XerC -
  EUC38_RS22880 trmFO 4562024..4563328 (-) 1305 WP_000213002.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EUC38_RS22885 topA 4563377..4565455 (-) 2079 WP_001286963.1 type I DNA topoisomerase -
  EUC38_RS22890 dprA 4565600..4566469 (-) 870 WP_000818060.1 DNA-processing protein DprA -
  EUC38_RS22895 sucD 4566558..4567460 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  EUC38_RS22900 sucC 4567480..4568640 (-) 1161 WP_001020791.1 ADP-forming succinate--CoA ligase subunit beta -
  EUC38_RS22905 - 4568835..4569608 (-) 774 WP_001194265.1 ribonuclease HII -
  EUC38_RS22910 ylqF 4569665..4570555 (-) 891 WP_000236704.1 ribosome biogenesis GTPase YlqF -
  EUC38_RS22915 lepB 4570576..4571127 (-) 552 WP_000711853.1 signal peptidase I -
  EUC38_RS22920 rplS 4571229..4571573 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  EUC38_RS22925 trmD 4571720..4572454 (-) 735 WP_000686903.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EUC38_RS22930 rimM 4572454..4572969 (-) 516 WP_000170278.1 ribosome maturation factor RimM -
  EUC38_RS22935 - 4573091..4573318 (-) 228 WP_000737401.1 KH domain-containing protein -
  EUC38_RS22940 rpsP 4573333..4573605 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  EUC38_RS22945 ffh 4573707..4575056 (-) 1350 WP_000863460.1 signal recognition particle protein -
  EUC38_RS22950 - 4575069..4575401 (-) 333 WP_000891062.1 putative DNA-binding protein -
  EUC38_RS22955 ftsY 4575535..4576524 (-) 990 WP_000007655.1 signal recognition particle-docking protein FtsY -
  EUC38_RS22960 smc 4576540..4580109 (-) 3570 WP_088053795.1 chromosome segregation protein SMC -
  EUC38_RS22965 rncS 4580256..4580993 (-) 738 WP_001146875.1 ribonuclease III -
  EUC38_RS22970 acpP 4581052..4581285 (-) 234 WP_000786062.1 acyl carrier protein -
  EUC38_RS22975 fabG 4581355..4582095 (-) 741 WP_000911773.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EUC38_RS22980 fabD 4582095..4583039 (-) 945 WP_000515899.1 ACP S-malonyltransferase -
  EUC38_RS22985 plsX 4583054..4584046 (-) 993 WP_016125148.1 phosphate acyltransferase PlsX -
  EUC38_RS22990 fapR 4584043..4584636 (-) 594 WP_000747348.1 transcription factor FapR -
  EUC38_RS22995 recG 4584725..4586773 (-) 2049 WP_001000816.1 ATP-dependent DNA helicase RecG -
  EUC38_RS23000 - 4587064..4588740 (-) 1677 WP_088053793.1 DAK2 domain-containing protein -
  EUC38_RS23005 - 4588763..4589125 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  EUC38_RS23010 rpmB 4589502..4589690 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  EUC38_RS23015 spoVM 4589764..4589844 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  EUC38_RS23020 - 4589911..4590591 (-) 681 WP_002026234.1 thiamine diphosphokinase -
  EUC38_RS23025 rpe 4590660..4591304 (-) 645 WP_000589974.1 ribulose-phosphate 3-epimerase -
  EUC38_RS23030 rsgA 4591307..4592188 (-) 882 WP_001113932.1 ribosome small subunit-dependent GTPase A -
  EUC38_RS23035 pknB 4592435..4594408 (-) 1974 WP_000904747.1 Stk1 family PASTA domain-containing Ser/Thr kinase -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=363418 EUC38_RS22860 WP_000421290.1 4558203..4558982(-) (codY) [Bacillus cereus strain DLOU-Tangshan]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=363418 EUC38_RS22860 WP_000421290.1 4558203..4558982(-) (codY) [Bacillus cereus strain DLOU-Tangshan]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGGAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCAAACGTATTCGTAGTTAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAAAACGAACGCATGAAGCAAATGCTTGCAGAACGTCAATTCCCAGAAGAATATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTGAACAGTGCTTACACAGCATTCCCAGTAGAAAACAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCGCGTAGTAAAGCTGTTGTTCAAATGGCAATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
TGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GCTCTGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAAGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment