Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E3S77_RS04140 Genome accession   NZ_CP047797
Coordinates   833459..834232 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain UP_426     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 828459..839232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S77_RS04105 (E3S77_04105) - 828712..829482 (-) 771 WP_047213393.1 isoprenyl transferase -
  E3S77_RS04110 (E3S77_04110) frr 829855..830409 (-) 555 WP_001280006.1 ribosome recycling factor -
  E3S77_RS04115 (E3S77_04115) pyrH 830428..831150 (-) 723 WP_000057330.1 UMP kinase -
  E3S77_RS04120 (E3S77_04120) tsf 831287..832168 (-) 882 WP_000201387.1 translation elongation factor Ts -
  E3S77_RS04125 (E3S77_04125) - 832203..832316 (-) 114 WP_001789890.1 hypothetical protein -
  E3S77_RS04130 (E3S77_04130) rpsB 832350..833117 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  E3S77_RS04135 (E3S77_04135) - 833316..833408 (-) 93 WP_031788481.1 hypothetical protein -
  E3S77_RS04140 (E3S77_04140) codY 833459..834232 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E3S77_RS04145 (E3S77_04145) hslU 834257..835660 (-) 1404 WP_047213391.1 ATP-dependent protease ATPase subunit HslU -
  E3S77_RS04150 (E3S77_04150) hslV 835726..836271 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E3S77_RS04155 (E3S77_04155) xerC 836268..837164 (-) 897 WP_001015611.1 tyrosine recombinase XerC -
  E3S77_RS04160 (E3S77_04160) trmFO 837581..838888 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=362826 E3S77_RS04140 WP_000055337.1 833459..834232(-) (codY) [Staphylococcus aureus strain UP_426]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=362826 E3S77_RS04140 WP_000055337.1 833459..834232(-) (codY) [Staphylococcus aureus strain UP_426]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428