Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E3S81_RS04425 Genome accession   NZ_CP047794
Coordinates   865524..866297 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain UP_551     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 860524..871297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S81_RS04390 (E3S81_04390) - 860777..861547 (-) 771 WP_047213393.1 isoprenyl transferase -
  E3S81_RS04395 (E3S81_04395) frr 861920..862474 (-) 555 WP_001280006.1 ribosome recycling factor -
  E3S81_RS04400 (E3S81_04400) pyrH 862493..863215 (-) 723 WP_000057330.1 UMP kinase -
  E3S81_RS04405 (E3S81_04405) tsf 863352..864233 (-) 882 WP_000201387.1 translation elongation factor Ts -
  E3S81_RS04410 (E3S81_04410) - 864268..864381 (-) 114 WP_001789890.1 hypothetical protein -
  E3S81_RS04415 (E3S81_04415) rpsB 864415..865182 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  E3S81_RS04420 (E3S81_04420) - 865381..865473 (-) 93 WP_031788481.1 hypothetical protein -
  E3S81_RS04425 (E3S81_04425) codY 865524..866297 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E3S81_RS04430 (E3S81_04430) hslU 866322..867725 (-) 1404 WP_160199102.1 ATP-dependent protease ATPase subunit HslU -
  E3S81_RS04435 (E3S81_04435) hslV 867791..868336 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E3S81_RS04440 (E3S81_04440) xerC 868333..869229 (-) 897 WP_001015611.1 tyrosine recombinase XerC -
  E3S81_RS04445 (E3S81_04445) trmFO 869646..870953 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=362563 E3S81_RS04425 WP_000055337.1 865524..866297(-) (codY) [Staphylococcus aureus strain UP_551]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=362563 E3S81_RS04425 WP_000055337.1 865524..866297(-) (codY) [Staphylococcus aureus strain UP_551]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428