Detailed information NTG0352685

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ES298_RS02540
• Genome accession: NZ_CP038253
• Coordinates: 502706..504382 (-)
• Length: 558 a.a.
• NCBI ID: WP_196299874.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 497706..509382

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS02510 (ES298_02645)	-	498040..498369 (-)	330	WP_000132572.1	hypothetical protein	-
ES298_RS02515 (ES298_02650)	-	498646..498984 (+)	339	WP_000682135.1	LytTR family DNA-binding domain-containing protein	-
ES298_RS02520 (ES298_02655)	comE/blpR	498989..499726 (+)	738	WP_001219120.1	LytTR family DNA-binding domain-containing protein	Regulator
ES298_RS02525 (ES298_02660)	-	499740..501080 (+)	1341	WP_001017638.1	sensor histidine kinase	-
ES298_RS02530 (ES298_02665)	blpC	501122..501277 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
ES298_RS02535 (ES298_02670)	-	501334..502695 (-)	1362	WP_001069091.1	bacteriocin secretion accessory protein	-
ES298_RS02540 (ES298_02675)	comA/nlmT	502706..504382 (-)	1677	WP_196299874.1	peptide cleavage/export ABC transporter	Regulator
ES298_RS11245	comA/nlmT	504276..504863 (-)	588	WP_001810228.1	cysteine peptidase family C39 domain-containing protein	Regulator
ES298_RS02545 (ES298_02680)	blpI	505145..505342 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
ES298_RS02550 (ES298_02690)	blpJ	505809..506078 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
ES298_RS02555 (ES298_02695)	blpU	506147..506377 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
ES298_RS02560 (ES298_02700)	-	506380..506499 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
ES298_RS02565 (ES298_02705)	-	506796..506960 (+)	165	WP_000727118.1	hypothetical protein	-
ES298_RS02570 (ES298_02710)	-	506957..507361 (+)	405	WP_000846944.1	hypothetical protein	-
ES298_RS02575 (ES298_02715)	-	507559..508363 (+)	805	Protein_514	IS5 family transposase	-
ES298_RS02580 (ES298_02720)	blpM	508513..508767 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
ES298_RS02585 (ES298_02725)	blpN	508783..508986 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
ES298_RS02590 (ES298_02735)	cipB	509230..509379 (+)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator

Sequence

Protein

• Length: 558 a.a.
• Molecular weight: 62923.20 Da
• Isoelectric Point: 6.7844

>NTDB_id=352685 ES298_RS02540 WP_196299874.1 502706..504382(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901929]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1677 bp

>NTDB_id=352685 ES298_RS02540 WP_196299874.1 502706..504382(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901929]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (341-490)

• ABC transporter transmembrane region (ABC_membrane) (10-279)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.89	99.821	0.728
comA	Streptococcus mitis NCTC 12261	67.204	100	0.672
comA	Streptococcus pneumoniae D39	66.846	100	0.668
comA	Streptococcus pneumoniae R6	66.846	100	0.668
comA	Streptococcus pneumoniae Rx1	66.846	100	0.668
comA	Streptococcus mitis SK321	66.667	100	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.547	100	0.667
comA	Streptococcus pneumoniae TIGR4	66.487	100	0.665