Detailed information NTG0352192

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3306_RS13335
• Genome accession: NZ_CP038183
• Coordinates: 2682451..2683338 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain MJ015
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2677451..2688338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3306_RS13305 (E3306_13885)	-	2677479..2677562 (+)	84	WP_031797553.1	hypothetical protein	-
E3306_RS13310 (E3306_13890)	-	2677670..2678167 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3306_RS13315 (E3306_13895)	-	2678177..2678437 (-)	261	WP_001789307.1	hypothetical protein	-
E3306_RS13320 (E3306_13905)	-	2678819..2678932 (-)	114	WP_011447078.1	hypothetical protein	-
E3306_RS13325 (E3306_13910)	-	2679591..2681591 (-)	2001	WP_000776733.1	ABC transporter permease	-
E3306_RS13330 (E3306_13915)	-	2681588..2682343 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3306_RS13335 (E3306_13920)	braS	2682451..2683338 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3306_RS13340 (E3306_13925)	braR	2683349..2684014 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3306_RS13345 (E3306_13930)	-	2684040..2684240 (-)	201	WP_000604727.1	hypothetical protein	-
E3306_RS13350 (E3306_13935)	-	2684438..2685862 (+)	1425	WP_000953744.1	alkaline phosphatase	-
E3306_RS14205 (E3306_13940)	-	2685922..2686023 (-)	102	WP_000731972.1	SE2200 family small protein	-
E3306_RS13360 (E3306_13945)	-	2686145..2686600 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3306_RS13365 (E3306_13950)	-	2686845..2687606 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=352192 E3306_RS13335 WP_000143419.1 2682451..2683338(-) (braS) [Staphylococcus aureus strain MJ015]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=352192 E3306_RS13335 WP_000143419.1 2682451..2683338(-) (braS) [Staphylococcus aureus strain MJ015]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997