Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   MGAS15252_RS06585 Genome accession   NC_017040
Coordinates   1347632..1348414 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes MGAS15252     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1342632..1353414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS06560 (MGAS15252_1352) gatB 1342729..1344168 (-) 1440 WP_011888633.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  MGAS15252_RS06565 (MGAS15252_1353) gatA 1344168..1345634 (-) 1467 WP_011018163.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  MGAS15252_RS06570 (MGAS15252_1354) gatC 1345634..1345936 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  MGAS15252_RS06575 (MGAS15252_1355) - 1346168..1346392 (-) 225 WP_227874710.1 putative PEP-binding protein -
  MGAS15252_RS06580 (MGAS15252_1357) - 1346931..1347485 (-) 555 WP_002992568.1 cysteine hydrolase family protein -
  MGAS15252_RS06585 (MGAS15252_1358) codY 1347632..1348414 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  MGAS15252_RS06590 (MGAS15252_1359) - 1348632..1349846 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  MGAS15252_RS06595 (MGAS15252_1360) - 1350077..1350529 (+) 453 WP_002992571.1 universal stress protein -
  MGAS15252_RS06600 (MGAS15252_1361) - 1350652..1352040 (-) 1389 WP_014407794.1 Cof-type HAD-IIB family hydrolase -
  MGAS15252_RS06605 (MGAS15252_1362) - 1352112..1353077 (+) 966 WP_014407795.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=35075 MGAS15252_RS06585 WP_002983278.1 1347632..1348414(-) (codY) [Streptococcus pyogenes MGAS15252]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=35075 MGAS15252_RS06585 WP_002983278.1 1347632..1348414(-) (codY) [Streptococcus pyogenes MGAS15252]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504