Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | NMO_RS04185 | Genome accession | NC_013016 |
| Coordinates | 811968..812636 (+) | Length | 222 a.a. |
| NCBI ID | WP_048816076.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis alpha14 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 810253..857720 | 811968..812636 | within | 0 |
Gene organization within MGE regions
Location: 810253..857720
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMO_RS04180 (NMO_0762) | dnaB | 810253..811659 (+) | 1407 | WP_015815448.1 | replicative DNA helicase | - |
| NMO_RS04185 (NMO_0763) | pilH | 811968..812636 (+) | 669 | WP_048816076.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NMO_RS04190 (NMO_0764) | pilV | 812666..813286 (+) | 621 | WP_015815450.1 | type IV pilus modification protein PilV | Machinery gene |
| NMO_RS04195 (NMO_0765) | pilJ | 813283..814248 (+) | 966 | WP_015815451.1 | PilW family protein | Machinery gene |
| NMO_RS04200 (NMO_0766) | pilK | 814227..814826 (+) | 600 | WP_015815452.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| NMO_RS04205 (NMO_0767) | pilX | 814831..815304 (+) | 474 | WP_002255852.1 | PilX family type IV pilin | Machinery gene |
| NMO_RS04210 (NMO_0768) | - | 817007..817375 (-) | 369 | Protein_803 | AzlC family ABC transporter permease | - |
| NMO_RS04215 (NMO_0769) | dut | 817575..818027 (+) | 453 | WP_015815455.1 | dUTP diphosphatase | - |
| NMO_RS04220 (NMO_0770) | dapC | 818103..819290 (+) | 1188 | WP_015815456.1 | succinyldiaminopimelate transaminase | - |
| NMO_RS15065 | - | 819379..819513 (+) | 135 | Protein_806 | IS5/IS1182 family transposase | - |
| NMO_RS04225 (NMO_0771) | yaaA | 819562..820341 (+) | 780 | WP_015815457.1 | peroxide stress protein YaaA | - |
| NMO_RS04240 (NMO_0772) | - | 820873..822069 (+) | 1197 | WP_002223440.1 | tyrosine-type recombinase/integrase | - |
| NMO_RS04245 (NMO_0773) | - | 822224..822604 (+) | 381 | WP_015815458.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NMO_RS04250 (NMO_0775) | - | 823006..823518 (+) | 513 | WP_002220685.1 | DUF4760 domain-containing protein | - |
| NMO_RS14385 (NMO_0776) | - | 823863..824039 (+) | 177 | WP_015815460.1 | hypothetical protein | - |
| NMO_RS04260 (NMO_0777) | - | 824191..825039 (+) | 849 | WP_015815461.1 | Bro-N domain-containing protein | - |
| NMO_RS04265 (NMO_0778) | - | 825097..825306 (-) | 210 | WP_002220687.1 | hypothetical protein | - |
| NMO_RS04270 | - | 825303..825443 (-) | 141 | WP_002225349.1 | hypothetical protein | - |
| NMO_RS04275 | - | 825443..825634 (-) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| NMO_RS04280 (NMO_0779) | - | 825637..825930 (-) | 294 | WP_002220689.1 | hypothetical protein | - |
| NMO_RS04285 (NMO_0780) | - | 825927..826187 (-) | 261 | WP_002223443.1 | NGO1622 family putative holin | - |
| NMO_RS04290 (NMO_0781) | - | 826222..826437 (-) | 216 | WP_015815462.1 | hypothetical protein | - |
| NMO_RS04295 (NMO_0782) | - | 826508..827362 (-) | 855 | WP_015815463.1 | YfdQ family protein | - |
| NMO_RS04300 (NMO_0783) | - | 827387..827746 (-) | 360 | WP_002220694.1 | hypothetical protein | - |
| NMO_RS04310 (NMO_0784) | - | 828258..828683 (-) | 426 | WP_048816202.1 | hypothetical protein | - |
| NMO_RS04315 (NMO_0785) | - | 828786..829502 (-) | 717 | WP_002220696.1 | S24 family peptidase | - |
| NMO_RS04320 (NMO_0786) | - | 829902..830249 (+) | 348 | WP_015815465.1 | hypothetical protein | - |
| NMO_RS04325 (NMO_0787) | - | 830364..832967 (+) | 2604 | WP_015815466.1 | primase-helicase family protein | - |
| NMO_RS04330 (NMO_0788) | - | 832964..833929 (-) | 966 | WP_002216744.1 | IS30-like element IS1655 family transposase | - |
| NMO_RS04335 (NMO_0789) | - | 834029..834283 (+) | 255 | WP_048816204.1 | hypothetical protein | - |
| NMO_RS04340 (NMO_0790) | - | 834292..835854 (+) | 1563 | WP_015815468.1 | phage portal protein | - |
| NMO_RS04345 (NMO_0791) | - | 835835..837727 (+) | 1893 | WP_002220704.1 | phage major capsid protein | - |
| NMO_RS04350 (NMO_0792) | - | 837785..838012 (+) | 228 | WP_002220705.1 | hypothetical protein | - |
| NMO_RS04355 (NMO_0793) | - | 838005..838307 (+) | 303 | WP_002244523.1 | hypothetical protein | - |
| NMO_RS04360 (NMO_0794) | - | 838288..838707 (+) | 420 | WP_015815470.1 | hypothetical protein | - |
| NMO_RS04365 (NMO_0795) | - | 838741..839382 (+) | 642 | WP_015815471.1 | phage tail protein | - |
| NMO_RS04370 (NMO_0796) | - | 839446..839757 (+) | 312 | WP_002220709.1 | phage tail assembly chaperone | - |
| NMO_RS04375 (NMO_0797) | - | 839805..840077 (+) | 273 | WP_015815472.1 | DUF1799 domain-containing protein | - |
| NMO_RS04380 (NMO_0798) | - | 840070..843288 (+) | 3219 | WP_015815473.1 | phage tail length tape measure family protein | - |
| NMO_RS04385 (NMO_0799) | - | 843310..843642 (+) | 333 | WP_002247809.1 | phage tail protein | - |
| NMO_RS04390 (NMO_0800) | - | 843639..844361 (+) | 723 | WP_015815474.1 | phage minor tail protein L | - |
| NMO_RS04395 (NMO_0801) | - | 844358..845113 (+) | 756 | WP_015815475.1 | C40 family peptidase | - |
| NMO_RS04400 (NMO_0802) | - | 845110..845832 (+) | 723 | WP_002220716.1 | tail assembly protein | - |
| NMO_RS04405 (NMO_0803) | - | 845968..850233 (+) | 4266 | WP_015815476.1 | phage tail protein | - |
| NMO_RS04410 (NMO_0804) | - | 850304..850750 (+) | 447 | WP_002241437.1 | hypothetical protein | - |
| NMO_RS14940 (NMO_0805) | - | 850767..850973 (+) | 207 | WP_002217448.1 | hypothetical protein | - |
| NMO_RS04420 (NMO_0806) | - | 851041..851412 (+) | 372 | WP_002217445.1 | hypothetical protein | - |
| NMO_RS04425 (NMO_0807) | - | 851476..851901 (+) | 426 | WP_002217444.1 | hypothetical protein | - |
| NMO_RS04430 | - | 851898..852173 (+) | 276 | WP_002217443.1 | hypothetical protein | - |
| NMO_RS04435 (NMO_0808) | - | 852312..852785 (+) | 474 | WP_015815477.1 | D-Ala-D-Ala carboxypeptidase family metallohydrolase | - |
| NMO_RS04440 (NMO_0809) | - | 852797..853333 (+) | 537 | WP_048816077.1 | hypothetical protein | - |
| NMO_RS04445 (NMO_0810) | - | 853553..853921 (-) | 369 | WP_015815479.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| NMO_RS14865 (NMO_0811) | - | 853918..854049 (-) | 132 | WP_015815480.1 | hypothetical protein | - |
| NMO_RS14390 (NMO_0813) | - | 854528..854680 (-) | 153 | WP_014575291.1 | hypothetical protein | - |
| NMO_RS04455 (NMO_0814) | - | 854670..854978 (-) | 309 | WP_015815482.1 | hypothetical protein | - |
| NMO_RS04460 (NMO_0815) | - | 855262..857487 (-) | 2226 | WP_015815483.1 | NADP-dependent isocitrate dehydrogenase | - |
| NMO_RS14275 (NMO_0816) | - | 857547..857720 (+) | 174 | WP_162470149.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 222 a.a. Molecular weight: 24908.56 Da Isoelectric Point: 10.0112
>NTDB_id=34966 NMO_RS04185 WP_048816076.1 811968..812636(+) (pilH) [Neisseria meningitidis alpha14]
MCTRKQQGFTLTELLIVMAIAAIMAMIALPNMSQWIASRRIASHAERVANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NKCDFGKKGQGMLAFGDKNGNKIYDNDTADVLLRSVVLNDDINNKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYTK
DQHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK
MCTRKQQGFTLTELLIVMAIAAIMAMIALPNMSQWIASRRIASHAERVANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NKCDFGKKGQGMLAFGDKNGNKIYDNDTADVLLRSVVLNDDINNKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYTK
DQHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK
Nucleotide
Download Length: 669 bp
>NTDB_id=34966 NMO_RS04185 WP_048816076.1 811968..812636(+) (pilH) [Neisseria meningitidis alpha14]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGATATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATAATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGATATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATAATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
86.425 |
99.55 |
0.86 |