Detailed information
Bioinformatically predicted
Overview
| Name | codY | Type | Regulator |
| Locus tag | EXW63_RS22325 | Genome accession | NZ_CP035997 |
| Coordinates | 4353033..4353812 (+) | Length | 259 a.a. |
| NCBI ID | WP_002014541.1 | Uniprot ID | - |
| Organism | Bacillus mycoides strain BPN36/3 | ||
| Function | repression of comK (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 4315649..4378518 | 4353033..4353812 | within | 0 |
Gene organization within MGE regions
Location: 4315649..4378518
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EXW63_RS22145 (EXW63_22640) | - | 4316652..4317404 (+) | 753 | WP_215551789.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| EXW63_RS22150 (EXW63_22645) | pknB | 4317413..4319386 (+) | 1974 | WP_002142922.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | - |
| EXW63_RS22155 (EXW63_22650) | rsgA | 4319657..4320538 (+) | 882 | WP_002014503.1 | ribosome small subunit-dependent GTPase A | - |
| EXW63_RS22160 (EXW63_22655) | rpe | 4320541..4321185 (+) | 645 | WP_002014505.1 | ribulose-phosphate 3-epimerase | - |
| EXW63_RS22165 (EXW63_22660) | - | 4321286..4321966 (+) | 681 | WP_002014506.1 | thiamine diphosphokinase | - |
| EXW63_RS22170 (EXW63_22665) | spoVM | 4322033..4322113 (+) | 81 | WP_001213599.1 | stage V sporulation protein SpoVM | - |
| EXW63_RS22175 (EXW63_22670) | rpmB | 4322187..4322375 (-) | 189 | WP_000124776.1 | 50S ribosomal protein L28 | - |
| EXW63_RS22180 (EXW63_22675) | - | 4322754..4323116 (+) | 363 | WP_002014507.1 | Asp23/Gls24 family envelope stress response protein | - |
| EXW63_RS22185 (EXW63_22680) | - | 4323139..4324815 (+) | 1677 | WP_215551790.1 | DAK2 domain-containing protein | - |
| EXW63_RS22190 (EXW63_22685) | recG | 4325240..4327288 (+) | 2049 | WP_002014510.1 | ATP-dependent DNA helicase RecG | - |
| EXW63_RS22195 (EXW63_22690) | fapR | 4327377..4327970 (+) | 594 | WP_000747354.1 | transcription factor FapR | - |
| EXW63_RS22200 (EXW63_22695) | plsX | 4327967..4328959 (+) | 993 | WP_002128828.1 | phosphate acyltransferase PlsX | - |
| EXW63_RS22205 (EXW63_22700) | fabD | 4328974..4329918 (+) | 945 | WP_215551791.1 | ACP S-malonyltransferase | - |
| EXW63_RS22210 (EXW63_22705) | fabG | 4329918..4330658 (+) | 741 | WP_002014514.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| EXW63_RS22215 (EXW63_22710) | acpP | 4330728..4330961 (+) | 234 | WP_002014515.1 | acyl carrier protein | - |
| EXW63_RS22220 (EXW63_22715) | rncS | 4331020..4331757 (+) | 738 | WP_002033792.1 | ribonuclease III | - |
| EXW63_RS22225 (EXW63_22720) | smc | 4331906..4335475 (+) | 3570 | WP_215551792.1 | chromosome segregation protein SMC | - |
| EXW63_RS22230 (EXW63_22725) | ftsY | 4335490..4336479 (+) | 990 | WP_002185064.1 | signal recognition particle-docking protein FtsY | - |
| EXW63_RS22235 (EXW63_22730) | - | 4336612..4336944 (+) | 333 | WP_002033794.1 | putative DNA-binding protein | - |
| EXW63_RS22240 (EXW63_22735) | ffh | 4336957..4338306 (+) | 1350 | WP_002014519.1 | signal recognition particle protein | - |
| EXW63_RS22245 (EXW63_22740) | rpsP | 4338407..4338679 (+) | 273 | WP_000268750.1 | 30S ribosomal protein S16 | - |
| EXW63_RS22250 (EXW63_22745) | - | 4338694..4338921 (+) | 228 | WP_002088196.1 | KH domain-containing protein | - |
| EXW63_RS22255 (EXW63_22750) | rimM | 4339043..4339558 (+) | 516 | WP_002014521.1 | ribosome maturation factor RimM | - |
| EXW63_RS22260 (EXW63_22755) | trmD | 4339558..4340292 (+) | 735 | WP_215551793.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| EXW63_RS22265 (EXW63_22760) | rplS | 4340439..4340783 (+) | 345 | WP_002014524.1 | 50S ribosomal protein L19 | - |
| EXW63_RS22270 (EXW63_22765) | lepB | 4340884..4341435 (+) | 552 | WP_002066791.1 | signal peptidase I | - |
| EXW63_RS22275 (EXW63_22770) | ylqF | 4341456..4342346 (+) | 891 | WP_002033795.1 | ribosome biogenesis GTPase YlqF | - |
| EXW63_RS22280 (EXW63_22775) | - | 4342402..4343175 (+) | 774 | WP_215551794.1 | ribonuclease HII | - |
| EXW63_RS22285 (EXW63_22780) | sucC | 4343369..4344529 (+) | 1161 | WP_002014529.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| EXW63_RS22290 (EXW63_22785) | sucD | 4344549..4345451 (+) | 903 | WP_000115186.1 | succinate--CoA ligase subunit alpha | - |
| EXW63_RS22295 (EXW63_22790) | dprA | 4345540..4346409 (+) | 870 | WP_215551795.1 | DNA-processing protein DprA | - |
| EXW63_RS22300 (EXW63_22795) | topA | 4346554..4348632 (+) | 2079 | WP_002088184.1 | type I DNA topoisomerase | - |
| EXW63_RS22305 (EXW63_22800) | trmFO | 4348681..4349985 (+) | 1305 | WP_215551796.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| EXW63_RS22310 (EXW63_22805) | xerC | 4350057..4350956 (+) | 900 | WP_078175468.1 | tyrosine recombinase XerC | - |
| EXW63_RS22315 (EXW63_22810) | hslV | 4350999..4351541 (+) | 543 | WP_002014538.1 | ATP-dependent protease proteolytic subunit HslV | - |
| EXW63_RS22320 (EXW63_22815) | hslU | 4351564..4352955 (+) | 1392 | WP_002014539.1 | ATP-dependent protease ATPase subunit HslU | - |
| EXW63_RS22325 (EXW63_22820) | codY | 4353033..4353812 (+) | 780 | WP_002014541.1 | GTP-sensing pleiotropic transcriptional regulator CodY | Regulator |
| EXW63_RS22330 (EXW63_22825) | rpsB | 4354167..4354868 (+) | 702 | WP_002088178.1 | 30S ribosomal protein S2 | - |
| EXW63_RS22335 (EXW63_22830) | tsf | 4354972..4355859 (+) | 888 | WP_002088177.1 | translation elongation factor Ts | - |
| EXW63_RS22340 (EXW63_22835) | pyrH | 4355926..4356648 (+) | 723 | WP_002014544.1 | UMP kinase | - |
| EXW63_RS22345 (EXW63_22840) | frr | 4356652..4357209 (+) | 558 | WP_000531506.1 | ribosome recycling factor | - |
| EXW63_RS22350 (EXW63_22845) | - | 4357295..4358071 (+) | 777 | WP_002014545.1 | isoprenyl transferase | - |
| EXW63_RS22355 (EXW63_22850) | cdsA | 4358089..4358880 (+) | 792 | WP_002088171.1 | phosphatidate cytidylyltransferase | - |
| EXW63_RS22360 (EXW63_22855) | dxr | 4358904..4360046 (+) | 1143 | WP_002014547.1 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase | - |
| EXW63_RS22365 (EXW63_22860) | rseP | 4360064..4361320 (+) | 1257 | WP_002088169.1 | RIP metalloprotease RseP | - |
| EXW63_RS22370 (EXW63_22865) | - | 4361430..4363130 (+) | 1701 | WP_078175371.1 | proline--tRNA ligase | - |
| EXW63_RS22375 (EXW63_22870) | - | 4363255..4367556 (+) | 4302 | WP_002033677.1 | PolC-type DNA polymerase III | - |
| EXW63_RS22380 (EXW63_22875) | rimP | 4367890..4368360 (+) | 471 | WP_002088165.1 | ribosome maturation factor RimP | - |
| EXW63_RS22385 (EXW63_22880) | nusA | 4368378..4369484 (+) | 1107 | WP_002014554.1 | transcription termination factor NusA | - |
| EXW63_RS22390 (EXW63_22885) | - | 4369496..4369768 (+) | 273 | WP_002088161.1 | YlxR family protein | - |
| EXW63_RS22395 (EXW63_22890) | - | 4369769..4370080 (+) | 312 | WP_002033679.1 | YlxQ family RNA-binding protein | - |
| EXW63_RS22400 (EXW63_22895) | infB | 4370085..4372151 (+) | 2067 | WP_002014558.1 | translation initiation factor IF-2 | - |
| EXW63_RS22405 (EXW63_22900) | - | 4372148..4372429 (+) | 282 | WP_063219178.1 | DUF503 family protein | - |
| EXW63_RS22410 (EXW63_22905) | rbfA | 4372445..4372801 (+) | 357 | WP_000776437.1 | 30S ribosome-binding factor RbfA | - |
| EXW63_RS22415 (EXW63_22910) | truB | 4372892..4373815 (+) | 924 | WP_002014562.1 | tRNA pseudouridine(55) synthase TruB | - |
| EXW63_RS22420 (EXW63_22915) | ribF | 4373859..4374830 (+) | 972 | WP_002128800.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EXW63_RS22425 (EXW63_22920) | rpsO | 4374931..4375200 (+) | 270 | WP_001229392.1 | 30S ribosomal protein S15 | - |
| EXW63_RS22430 (EXW63_22925) | pnp | 4375362..4377515 (+) | 2154 | WP_002033682.1 | polyribonucleotide nucleotidyltransferase | - |
Sequence
Protein
Download Length: 259 a.a. Molecular weight: 28774.99 Da Isoelectric Point: 4.7251
>NTDB_id=345699 EXW63_RS22325 WP_002014541.1 4353033..4353812(+) (codY) [Bacillus mycoides strain BPN36/3]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKHMLAERQFPEEYTQSLF
NVTETSSNLGVDSDYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKHMLAERQFPEEYTQSLF
NVTETSSNLGVDSDYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN
Nucleotide
Download Length: 780 bp
>NTDB_id=345699 EXW63_RS22325 WP_002014541.1 4353033..4353812(+) (codY) [Bacillus mycoides strain BPN36/3]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAGAT
GTCTGACACAATGTGTGAAGTAATTGAAGCGAACGTGTTCGTTGTAAGTCGTCGCGGTAAATTATTAGGATATGCGATTC
ACCAACAAATCGAAAACGAACGTATGAAGCACATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACGCAAAGTTTATTC
AATGTTACAGAAACATCTTCAAATTTAGGTGTGGATAGTGACTACACAGCATTCCCAGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACACTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGACGATGATTTAATTCTTGCTGAATACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCGGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAGAT
GTCTGACACAATGTGTGAAGTAATTGAAGCGAACGTGTTCGTTGTAAGTCGTCGCGGTAAATTATTAGGATATGCGATTC
ACCAACAAATCGAAAACGAACGTATGAAGCACATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACGCAAAGTTTATTC
AATGTTACAGAAACATCTTCAAATTTAGGTGTGGATAGTGACTACACAGCATTCCCAGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACACTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGACGATGATTTAATTCTTGCTGAATACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCGGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| codY | Bacillus subtilis subsp. subtilis str. 168 |
81.081 |
100 |
0.811 |
| codY | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.275 |
98.456 |
0.456 |