Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EXW32_RS18820 Genome accession   NZ_CP035994
Coordinates   3756071..3756850 (-) Length   259 a.a.
NCBI ID   WP_002014541.1    Uniprot ID   -
Organism   Bacillus mycoides strain BPN36/2     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3724547..3791570 3756071..3756850 within 0


Gene organization within MGE regions


Location: 3724547..3791570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW32_RS18675 (EXW32_19110) dapA 3724611..3725489 (-) 879 WP_002014579.1 4-hydroxy-tetrahydrodipicolinate synthase -
  EXW32_RS18680 (EXW32_19115) dapG 3725501..3726733 (-) 1233 WP_002088068.1 aspartate kinase -
  EXW32_RS18685 (EXW32_19120) asd 3726757..3727803 (-) 1047 WP_002014577.1 aspartate-semialdehyde dehydrogenase -
  EXW32_RS18690 (EXW32_19125) dpaB 3727953..3728552 (-) 600 WP_002111357.1 dipicolinate synthase subunit B -
  EXW32_RS18695 (EXW32_19130) dpaA 3728549..3729451 (-) 903 WP_002128797.1 dipicolinic acid synthetase subunit A -
  EXW32_RS18700 (EXW32_19135) - 3729624..3729872 (-) 249 WP_215585547.1 YlmC/YmxH family sporulation protein -
  EXW32_RS18705 (EXW32_19140) - 3730008..3731249 (-) 1242 WP_002088150.1 pitrilysin family protein -
  EXW32_RS18710 (EXW32_19145) - 3731336..3732235 (-) 900 WP_002128798.1 polysaccharide deacetylase family protein -
  EXW32_RS18715 (EXW32_19150) pnp 3732390..3734543 (-) 2154 WP_002128799.1 polyribonucleotide nucleotidyltransferase -
  EXW32_RS18720 (EXW32_19155) rpsO 3734705..3734974 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  EXW32_RS18725 (EXW32_19160) ribF 3735075..3736046 (-) 972 WP_002128800.1 bifunctional riboflavin kinase/FAD synthetase -
  EXW32_RS18730 (EXW32_19165) truB 3736090..3737013 (-) 924 WP_215563592.1 tRNA pseudouridine(55) synthase TruB -
  EXW32_RS18735 (EXW32_19170) rbfA 3737104..3737460 (-) 357 WP_000776437.1 30S ribosome-binding factor RbfA -
  EXW32_RS18740 (EXW32_19175) - 3737476..3737757 (-) 282 WP_002088157.1 DUF503 family protein -
  EXW32_RS18745 (EXW32_19180) infB 3737754..3739820 (-) 2067 WP_002014558.1 translation initiation factor IF-2 -
  EXW32_RS18750 (EXW32_19185) - 3739825..3740136 (-) 312 WP_001286519.1 YlxQ family RNA-binding protein -
  EXW32_RS18755 (EXW32_19190) - 3740137..3740409 (-) 273 WP_002088161.1 YlxR family protein -
  EXW32_RS18760 (EXW32_19195) nusA 3740421..3741527 (-) 1107 WP_002014554.1 transcription termination factor NusA -
  EXW32_RS18765 (EXW32_19200) rimP 3741545..3742015 (-) 471 WP_002088165.1 ribosome maturation factor RimP -
  EXW32_RS18770 (EXW32_19205) - 3742349..3746650 (-) 4302 WP_002033677.1 PolC-type DNA polymerase III -
  EXW32_RS18775 (EXW32_19210) - 3746775..3748475 (-) 1701 WP_002128803.1 proline--tRNA ligase -
  EXW32_RS18780 (EXW32_19215) rseP 3748585..3749841 (-) 1257 WP_002088169.1 RIP metalloprotease RseP -
  EXW32_RS18785 (EXW32_19220) dxr 3749859..3751001 (-) 1143 WP_002014547.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  EXW32_RS18790 (EXW32_19225) cdsA 3751025..3751816 (-) 792 WP_002088171.1 phosphatidate cytidylyltransferase -
  EXW32_RS18795 (EXW32_19230) uppS 3751834..3752610 (-) 777 WP_033731196.1 isoprenyl transferase -
  EXW32_RS18800 (EXW32_19235) frr 3752696..3753253 (-) 558 WP_000531506.1 ribosome recycling factor -
  EXW32_RS18805 (EXW32_19240) pyrH 3753257..3753979 (-) 723 WP_002014544.1 UMP kinase -
  EXW32_RS18810 (EXW32_19245) tsf 3754046..3754933 (-) 888 WP_002088177.1 translation elongation factor Ts -
  EXW32_RS18815 (EXW32_19250) rpsB 3755016..3755717 (-) 702 WP_002185070.1 30S ribosomal protein S2 -
  EXW32_RS18820 (EXW32_19255) codY 3756071..3756850 (-) 780 WP_002014541.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EXW32_RS18825 (EXW32_19260) hslU 3756928..3758319 (-) 1392 WP_002014539.1 ATP-dependent protease ATPase subunit HslU -
  EXW32_RS18830 (EXW32_19265) hslV 3758342..3758884 (-) 543 WP_002014538.1 ATP-dependent protease proteolytic subunit HslV -
  EXW32_RS18835 (EXW32_19270) xerC 3758927..3759826 (-) 900 WP_078175468.1 tyrosine recombinase XerC -
  EXW32_RS18840 (EXW32_19275) trmFO 3759898..3761202 (-) 1305 WP_002066796.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EXW32_RS18845 (EXW32_19280) topA 3761251..3763329 (-) 2079 WP_002088184.1 type I DNA topoisomerase -
  EXW32_RS18850 (EXW32_19285) dprA 3763474..3764343 (-) 870 WP_002167750.1 DNA-processing protein DprA -
  EXW32_RS18855 (EXW32_19290) sucD 3764432..3765334 (-) 903 WP_002033796.1 succinate--CoA ligase subunit alpha -
  EXW32_RS18860 (EXW32_19295) sucC 3765354..3766514 (-) 1161 WP_002014529.1 ADP-forming succinate--CoA ligase subunit beta -
  EXW32_RS18865 (EXW32_19300) - 3766708..3767481 (-) 774 WP_002014527.1 ribonuclease HII -
  EXW32_RS18870 (EXW32_19305) ylqF 3767537..3768427 (-) 891 WP_002128821.1 ribosome biogenesis GTPase YlqF -
  EXW32_RS18875 (EXW32_19310) lepB 3768448..3768999 (-) 552 WP_215585548.1 signal peptidase I -
  EXW32_RS18880 (EXW32_19315) rplS 3769100..3769444 (-) 345 WP_002014524.1 50S ribosomal protein L19 -
  EXW32_RS18885 (EXW32_19320) trmD 3769591..3770325 (-) 735 WP_002014522.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EXW32_RS18890 (EXW32_19325) rimM 3770325..3770840 (-) 516 WP_002014521.1 ribosome maturation factor RimM -
  EXW32_RS18895 (EXW32_19330) - 3770962..3771189 (-) 228 WP_002088196.1 KH domain-containing protein -
  EXW32_RS18900 (EXW32_19335) rpsP 3771204..3771476 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  EXW32_RS18905 (EXW32_19340) ffh 3771577..3772926 (-) 1350 WP_002014519.1 signal recognition particle protein -
  EXW32_RS18910 (EXW32_19345) - 3772939..3773271 (-) 333 WP_000891061.1 putative DNA-binding protein -
  EXW32_RS18915 (EXW32_19350) ftsY 3773404..3774393 (-) 990 WP_002088200.1 signal recognition particle-docking protein FtsY -
  EXW32_RS18920 (EXW32_19355) smc 3774408..3777977 (-) 3570 WP_201056863.1 chromosome segregation protein SMC -
  EXW32_RS18925 (EXW32_19360) rncS 3778126..3778863 (-) 738 WP_002033792.1 ribonuclease III -
  EXW32_RS18930 (EXW32_19365) acpP 3778922..3779155 (-) 234 WP_002014515.1 acyl carrier protein -
  EXW32_RS18935 (EXW32_19370) fabG 3779225..3779965 (-) 741 WP_002014514.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EXW32_RS18940 (EXW32_19375) fabD 3779965..3780909 (-) 945 WP_002128825.1 ACP S-malonyltransferase -
  EXW32_RS18945 (EXW32_19380) plsX 3780924..3781916 (-) 993 WP_002128828.1 phosphate acyltransferase PlsX -
  EXW32_RS18950 (EXW32_19385) fapR 3781913..3782506 (-) 594 WP_000747354.1 transcription factor FapR -
  EXW32_RS18955 (EXW32_19390) recG 3782595..3784643 (-) 2049 WP_002014510.1 ATP-dependent DNA helicase RecG -
  EXW32_RS18960 (EXW32_19395) - 3785078..3786754 (-) 1677 WP_002128829.1 DAK2 domain-containing protein -
  EXW32_RS18965 (EXW32_19400) - 3786777..3787139 (-) 363 WP_002014507.1 Asp23/Gls24 family envelope stress response protein -
  EXW32_RS18970 (EXW32_19405) rpmB 3787518..3787706 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  EXW32_RS18975 (EXW32_19410) spoVM 3787780..3787860 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  EXW32_RS18980 (EXW32_19415) - 3787927..3788607 (-) 681 WP_002014506.1 thiamine diphosphokinase -
  EXW32_RS18985 (EXW32_19420) rpe 3788708..3789352 (-) 645 WP_002014505.1 ribulose-phosphate 3-epimerase -
  EXW32_RS18990 (EXW32_19425) rsgA 3789355..3790236 (-) 882 WP_002014503.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.99 Da        Isoelectric Point: 4.7251

>NTDB_id=345629 EXW32_RS18820 WP_002014541.1 3756071..3756850(-) (codY) [Bacillus mycoides strain BPN36/2]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKHMLAERQFPEEYTQSLF
NVTETSSNLGVDSDYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=345629 EXW32_RS18820 WP_002014541.1 3756071..3756850(-) (codY) [Bacillus mycoides strain BPN36/2]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAGAT
GTCTGACACAATGTGTGAAGTAATTGAAGCGAACGTGTTCGTTGTAAGTCGTCGCGGTAAATTATTAGGATATGCGATTC
ACCAACAAATCGAAAACGAACGTATGAAGCACATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACGCAAAGTTTATTC
AATGTTACAGAAACATCTTCAAATTTAGGTGTGGATAGTGACTACACAGCATTCCCGGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACACTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGACGATGATTTAATTCTTGCTGAATACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTCGGAATTACTC
GTTCGGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY helix-turn-helix domain (HTH_CodY)

(198-255)

CodY GAF-like domain (CodY)

(2-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.275

98.456

0.456

Multiple sequence alignment