Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   GFB63_RS03390 Genome accession   NZ_CP045596
Coordinates   668569..668862 (-) Length   97 a.a.
NCBI ID   WP_084829136.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 663569..673862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS03355 (GFB63_03445) - 663971..664414 (-) 444 WP_041829335.1 hypothetical protein -
  GFB63_RS10520 (GFB63_03450) - 664488..664826 (-) 339 WP_228024408.1 CPBP family intramembrane glutamic endopeptidase -
  GFB63_RS10525 (GFB63_03455) - 664870..665145 (-) 276 WP_084826166.1 CAAX protease -
  GFB63_RS03365 (GFB63_03460) - 665157..665354 (-) 198 WP_084826167.1 helix-turn-helix transcriptional regulator -
  GFB63_RS03370 (GFB63_03465) - 665603..666796 (-) 1194 WP_084826168.1 acetate kinase -
  GFB63_RS03375 (GFB63_03470) comGH 666852..667808 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  GFB63_RS03380 (GFB63_03475) comGG 667853..668170 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG Machinery gene
  GFB63_RS03385 (GFB63_03480) comGF 668148..668585 (-) 438 WP_084829135.1 competence type IV pilus minor pilin ComGF Machinery gene
  GFB63_RS03390 (GFB63_03485) comGE 668569..668862 (-) 294 WP_084829136.1 competence type IV pilus minor pilin ComGE Machinery gene
  GFB63_RS03395 (GFB63_03490) comGD 668834..669262 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  GFB63_RS03400 (GFB63_03495) comGC 669222..669548 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  GFB63_RS03405 (GFB63_03500) comGB 669545..670645 (-) 1101 WP_144239090.1 competence type IV pilus assembly protein ComGB Machinery gene
  GFB63_RS03410 (GFB63_03505) comGA 670527..671468 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  GFB63_RS03415 (GFB63_03510) - 671549..671911 (-) 363 WP_023909982.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.70 Da        Isoelectric Point: 10.2202

>NTDB_id=345208 GFB63_RS03390 WP_084829136.1 668569..668862(-) (comGE) [Streptococcus thermophilus strain TK-P3A]
MVNIKRRSLRGYILIESLIAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTNQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=345208 GFB63_RS03390 WP_084829136.1 668569..668862(-) (comGE) [Streptococcus thermophilus strain TK-P3A]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGCCTGATAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAATCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

42.268

100

0.423
  comGE Streptococcus mutans UA159

42.268

100

0.423
  comGE Lactococcus lactis subsp. cremoris KW2

37.113

100

0.371

Multiple sequence alignment