Detailed information NTG0345187

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: GFB63_RS02215
• Genome accession: NZ_CP045596
• Coordinates: 443585..444370 (-)
• Length: 261 a.a.
• NCBI ID: WP_084826115.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 438585..449370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS02180 (GFB63_02250)	gatC	438650..438952 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
GFB63_RS02185 (GFB63_02255)	-	439127..439345 (-)	219	WP_014621899.1	glycosyl transferase	-
GFB63_RS10870	-	439284..439448 (-)	165	WP_231838381.1	glycosyltransferase	-
GFB63_RS02195 (GFB63_02265)	-	439885..441326 (-)	1442	Protein_446	6-phospho-beta-glucosidase	-
GFB63_RS02200 (GFB63_02270)	msrA	441479..441988 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
GFB63_RS02205 (GFB63_02275)	-	442000..442848 (-)	849	WP_041828318.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
GFB63_RS02210 (GFB63_02280)	-	442971..443522 (-)	552	WP_111679685.1	cysteine hydrolase family protein	-
GFB63_RS02215 (GFB63_02285)	codY	443585..444370 (-)	786	WP_084826115.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
GFB63_RS02220 (GFB63_02290)	-	444630..445844 (-)	1215	WP_193838363.1	pyridoxal phosphate-dependent aminotransferase	-
GFB63_RS02225 (GFB63_02295)	-	446198..446650 (+)	453	WP_084826116.1	universal stress protein	-
GFB63_RS02230 (GFB63_02300)	-	446827..447401 (+)	575	Protein_453	IS30 family transposase	-
GFB63_RS10425	-	447473..448081 (-)	609	WP_223899685.1	hypothetical protein	-
GFB63_RS02240 (GFB63_02310)	pflA	448293..449093 (-)	801	WP_193838364.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28920.07 Da
• Isoelectric Point: 4.4713

>NTDB_id=345187 GFB63_RS02215 WP_084826115.1 443585..444370(-) (codY) [Streptococcus thermophilus strain TK-P3A]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEEFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=345187 GFB63_RS02215 WP_084826115.1 443585..444370(-) (codY) [Streptococcus thermophilus strain TK-P3A]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAGAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACATTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	52.632	94.636	0.498