Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ERW13_RS02505 Genome accession   NZ_CP035791
Coordinates   448021..449091 (+) Length   356 a.a.
NCBI ID   WP_000776422.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 592     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 443021..454091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERW13_RS02475 - 443444..444907 (+) 1464 WP_001017852.1 rhomboid family intramembrane serine protease -
  ERW13_RS02480 - 444888..445091 (+) 204 WP_000087561.1 YqgQ family protein -
  ERW13_RS02485 - 445088..446074 (+) 987 WP_000161311.1 ROK family glucokinase -
  ERW13_RS02490 - 446074..446403 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ERW13_RS02495 - 446400..447023 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  ERW13_RS02500 comGA 447075..448049 (+) 975 WP_000697216.1 competence type IV pilus ATPase ComGA Machinery gene
  ERW13_RS02505 comGB 448021..449091 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  ERW13_RS02510 comGC 449105..449416 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ERW13_RS02515 comGD 449394..449840 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  ERW13_RS02520 comGE 449827..450126 (+) 300 WP_000844410.1 hypothetical protein Machinery gene
  ERW13_RS02525 comGF 450044..450541 (+) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  ERW13_RS02530 - 450638..450784 (+) 147 WP_001792109.1 hypothetical protein -
  ERW13_RS02535 - 450774..451298 (+) 525 WP_001015120.1 shikimate kinase -
  ERW13_RS02540 gcvT 451457..452548 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  ERW13_RS02545 gcvPA 452568..453914 (+) 1347 WP_000019691.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41447.84 Da        Isoelectric Point: 10.0606

>NTDB_id=344434 ERW13_RS02505 WP_000776422.1 448021..449091(+) (comGB) [Staphylococcus aureus strain 592]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=344434 ERW13_RS02505 WP_000776422.1 448021..449091(+) (comGB) [Staphylococcus aureus strain 592]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

100

100

1
  comGB Staphylococcus aureus N315

100

100

1

Multiple sequence alignment