Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   FSA40_RS08530 Genome accession   NZ_CP044493
Coordinates   1684831..1685616 (-) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans strain MD     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1679831..1690616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS08510 (FSA40_1707) gatA 1680371..1681837 (-) 1467 WP_002274738.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  FSA40_RS08515 (FSA40_1708) gatC 1681837..1682139 (-) 303 WP_002263475.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  FSA40_RS08520 (FSA40_1709) aspS 1682266..1684017 (-) 1752 WP_151416418.1 aspartate--tRNA ligase -
  FSA40_RS08525 (FSA40_1710) - 1684278..1684829 (-) 552 WP_002306824.1 isochorismatase family cysteine hydrolase -
  FSA40_RS08530 (FSA40_1711) codY 1684831..1685616 (-) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  FSA40_RS08535 (FSA40_1712) - 1685725..1686939 (-) 1215 WP_002263471.1 pyridoxal phosphate-dependent aminotransferase -
  FSA40_RS08540 (FSA40_1713) - 1687116..1687652 (+) 537 WP_002263470.1 biotin transporter BioY -
  FSA40_RS08545 (FSA40_1714) - 1687750..1688199 (+) 450 WP_002263469.1 universal stress protein -
  FSA40_RS08550 (FSA40_1715) - 1688477..1689862 (-) 1386 WP_301337314.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=342933 FSA40_RS08530 WP_002263472.1 1684831..1685616(-) (codY) [Streptococcus mutans strain MD]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=342933 FSA40_RS08530 WP_002263472.1 1684831..1685616(-) (codY) [Streptococcus mutans strain MD]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCAGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACTATTGCTCCCATCTATGGCGGTGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTTTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAAGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACATATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471