Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F7D06_RS10220 Genome accession   NZ_CP044311
Coordinates   2012601..2013257 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain RM13752     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007601..2018257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7D06_RS10180 (F7D06_10320) - 2008111..2008371 (+) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -
  F7D06_RS10185 (F7D06_10325) - 2008561..2008701 (+) 141 WP_000078920.1 Hok/Gef family protein -
  F7D06_RS10190 (F7D06_10330) - 2008891..2009172 (-) 282 WP_071529678.1 hypothetical protein -
  F7D06_RS10210 (F7D06_10350) pgsA 2010167..2010715 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F7D06_RS10215 (F7D06_10355) uvrC 2010772..2012604 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  F7D06_RS10220 (F7D06_10360) letA 2012601..2013257 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F7D06_RS26975 - 2013399..2013470 (+) 72 Protein_2028 transcriptional regulator -
  F7D06_RS10225 (F7D06_10365) yecU 2013553..2013729 (+) 177 WP_000590347.1 protein YecU -
  F7D06_RS10230 (F7D06_10370) yecF 2013716..2013940 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  F7D06_RS10235 (F7D06_10375) sdiA 2014007..2014729 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  F7D06_RS10240 (F7D06_10380) tcyN 2014959..2015711 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F7D06_RS10245 (F7D06_10385) tcyL 2015708..2016376 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  F7D06_RS10250 (F7D06_10390) dcyD 2016391..2017377 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=341767 F7D06_RS10220 WP_000611335.1 2012601..2013257(-) (letA) [Escherichia coli strain RM13752]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=341767 F7D06_RS10220 WP_000611335.1 2012601..2013257(-) (letA) [Escherichia coli strain RM13752]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment