Detailed information NTG0341723

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ETT59_RS09025
• Genome accession: NZ_CP035440
• Coordinates: 1187588..1188454 (-)
• Length: 288 a.a.
• NCBI ID: WP_063629066.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm124
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1182588..1193454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT59_RS05965 (ETT59_05970)	-	1182780..1183166 (-)	387	WP_011528464.1	YbgA family protein	-
ETT59_RS05970 (ETT59_05975)	-	1183159..1183536 (-)	378	WP_002993028.1	OsmC family protein	-
ETT59_RS05975 (ETT59_05980)	pheT	1183647..1186052 (-)	2406	WP_136305943.1	phenylalanine--tRNA ligase subunit beta	-
ETT59_RS05980 (ETT59_05985)	pheS	1186262..1187305 (-)	1044	WP_063629067.1	phenylalanine--tRNA ligase subunit alpha	-
ETT59_RS09025	endA	1187588..1188454 (-)	867	WP_063629066.1	DNA/RNA non-specific endonuclease	Machinery gene
ETT59_RS05990 (ETT59_05995)	-	1188490..1188678 (-)	189	WP_002985226.1	DNA-directed RNA polymerase subunit beta	-
ETT59_RS05995 (ETT59_06000)	murA	1188682..1189953 (-)	1272	WP_002994428.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ETT59_RS06000 (ETT59_06005)	-	1190018..1190242 (-)	225	WP_002985230.1	DUF1146 family protein	-
ETT59_RS06005 (ETT59_06010)	-	1190541..1190957 (-)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
ETT59_RS06010 (ETT59_06015)	atpD	1190970..1192376 (-)	1407	WP_011017611.1	F0F1 ATP synthase subunit beta	-
ETT59_RS06015 (ETT59_06020)	-	1192538..1193413 (-)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32068.49 Da
• Isoelectric Point: 10.4166

>NTDB_id=341723 ETT59_RS09025 WP_063629066.1 1187588..1188454(-) (endA) [Streptococcus pyogenes strain emm124]
MLTRKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLTAKVASPPYANNKTKWVQEQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQVNKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTGQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=341723 ETT59_RS09025 WP_063629066.1 1187588..1188454(-) (endA) [Streptococcus pyogenes strain emm124]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCATCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTGACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATCTAACTGCTAAGGTAGC
CAGTCCGCCTTATGCCAACAATAAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTTAAGCCAGCAGGTTGGCACCAATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTTGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGTAAATAAACCCTACTCGA
CAGGTCAGAACTACTATGAAGGTTTAGTACGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATCGGACGGGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (120-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	59.916	82.292	0.493
endA	Streptococcus pneumoniae D39	59.916	82.292	0.493
endA	Streptococcus pneumoniae R6	59.916	82.292	0.493
endA	Streptococcus pneumoniae TIGR4	59.916	82.292	0.493