Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ETT68_RS03315 Genome accession   NZ_CP035431
Coordinates   612691..613539 (+) Length   282 a.a.
NCBI ID   WP_168473480.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm105     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 607691..618539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT68_RS03285 (ETT68_03275) - 607732..608607 (+) 876 WP_002985236.1 F0F1 ATP synthase subunit gamma -
  ETT68_RS03290 (ETT68_03280) atpD 608769..610175 (+) 1407 WP_011017611.1 F0F1 ATP synthase subunit beta -
  ETT68_RS03295 (ETT68_03285) - 610188..610604 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  ETT68_RS03300 (ETT68_03290) - 610903..611127 (+) 225 WP_002985230.1 DUF1146 family protein -
  ETT68_RS03305 (ETT68_03295) murA 611192..612463 (+) 1272 WP_002994428.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ETT68_RS03310 (ETT68_03300) - 612467..612655 (+) 189 WP_011017613.1 DNA-directed RNA polymerase subunit beta -
  ETT68_RS03315 (ETT68_03305) endA 612691..613539 (+) 849 WP_168473480.1 DNA/RNA non-specific endonuclease Machinery gene
  ETT68_RS03320 (ETT68_03310) pheS 613840..614883 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  ETT68_RS03325 (ETT68_03315) pheT 615093..617498 (+) 2406 WP_109991752.1 phenylalanine--tRNA ligase subunit beta -
  ETT68_RS03330 (ETT68_03320) - 617608..617985 (+) 378 WP_002993028.1 OsmC family protein -
  ETT68_RS03335 (ETT68_03325) - 617978..618364 (+) 387 WP_002990406.1 YbgA family protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31349.72 Da        Isoelectric Point: 10.4386

>NTDB_id=341223 ETT68_RS03315 WP_168473480.1 612691..613539(+) (endA) [Streptococcus pyogenes strain emm105]
MLTRKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLTAKVASPPYANNETKWVQEQKVPKRANALLAKSTRQYQDRSQLKKGYRSFKPVGWYRL
HHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQAGLTVDYRTG

Nucleotide


Download         Length: 849 bp        

>NTDB_id=341223 ETT68_RS03315 WP_168473480.1 612691..613539(+) (endA) [Streptococcus pyogenes strain emm105]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTGACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAACTGCTAAGGTAGC
CAGTCCGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCCAACGCTTTACTTGCTA
AGTCAACCCGGCAATATCAAGACCGTTCACAACTTAAGAAAGGTTACCGTTCATTTAAGCCAGTAGGTTGGTACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTTGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAATTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGTGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAAGCAGGATTGACCGTTGACTATCGGACGGGATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(114-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

59.227

82.624

0.489
  endA Streptococcus pneumoniae D39

59.227

82.624

0.489
  endA Streptococcus pneumoniae R6

59.227

82.624

0.489
  endA Streptococcus pneumoniae TIGR4

59.227

82.624

0.489

Multiple sequence alignment