Detailed information NTG0340271

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FOB78_RS05220
• Genome accession: NZ_CP044090
• Coordinates: 1044035..1044820 (-)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain FDAARGOS_670
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1039035..1049820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB78_RS05190 (FOB78_05190)	-	1039074..1039580 (-)	507	Protein_991	PTS sugar transporter subunit IIC	-
FOB78_RS05195 (FOB78_05195)	-	1039773..1040657 (+)	885	WP_000354840.1	LysR family transcriptional regulator	-
FOB78_RS05200 (FOB78_05200)	-	1040694..1041512 (-)	819	WP_000601007.1	hypothetical protein	-
FOB78_RS05205 (FOB78_05205)	-	1041676..1042449 (-)	774	WP_000012390.1	ABC transporter permease	-
FOB78_RS05210 (FOB78_05210)	-	1042446..1043102 (-)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
FOB78_RS05215 (FOB78_05215)	-	1043319..1043957 (+)	639	WP_000478529.1	VTT domain-containing protein	-
FOB78_RS05220 (FOB78_05220)	endA	1044035..1044820 (-)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
FOB78_RS05225 (FOB78_05225)	-	1045081..1046526 (+)	1446	WP_032458606.1	FAD/NAD(P)-binding protein	-
FOB78_RS05230 (FOB78_05230)	-	1046583..1047254 (-)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
FOB78_RS05235 (FOB78_05235)	-	1047351..1047671 (-)	321	WP_001865677.1	hypothetical protein	-
FOB78_RS05240 (FOB78_05240)	-	1047680..1047808 (-)	129	WP_000962057.1	hypothetical protein	-
FOB78_RS05245 (FOB78_05245)	-	1047909..1048175 (-)	267	WP_001865676.1	hypothetical protein	-
FOB78_RS05250 (FOB78_05250)	-	1048260..1048703 (-)	444	WP_001048166.1	hypothetical protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=340271 FOB78_RS05220 WP_000825431.1 1044035..1044820(-) (endA) [Streptococcus agalactiae strain FDAARGOS_670]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=340271 FOB78_RS05220 WP_000825431.1 1044035..1044820(-) (endA) [Streptococcus agalactiae strain FDAARGOS_670]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATCTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391