Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | EQW00_RS00395 | Genome accession | NZ_CP035288 |
| Coordinates | 83251..84879 (-) | Length | 542 a.a. |
| NCBI ID | WP_001631035.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain ATCC 14990 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 47199..102102 | 83251..84879 | within | 0 |
Gene organization within MGE regions
Location: 47199..102102
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQW00_RS00205 (EQW00_00205) | - | 47199..48878 (+) | 1680 | WP_083553768.1 | recombinase family protein | - |
| EQW00_RS00210 (EQW00_00210) | - | 48967..49305 (+) | 339 | WP_032604336.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| EQW00_RS00220 (EQW00_00220) | - | 49399..49710 (+) | 312 | WP_032604337.1 | DUF960 family protein | - |
| EQW00_RS00225 (EQW00_00225) | - | 49726..50229 (+) | 504 | WP_002437518.1 | DUF1643 domain-containing protein | - |
| EQW00_RS00230 (EQW00_00230) | - | 50243..50464 (+) | 222 | WP_002437519.1 | hypothetical protein | - |
| EQW00_RS00235 (EQW00_00235) | - | 50615..51181 (+) | 567 | WP_002437520.1 | hypothetical protein | - |
| EQW00_RS00240 (EQW00_00240) | - | 51259..54378 (-) | 3120 | WP_083553769.1 | type I restriction endonuclease subunit R | - |
| EQW00_RS00245 (EQW00_00245) | - | 54362..55564 (-) | 1203 | WP_083553770.1 | restriction endonuclease subunit S | - |
| EQW00_RS00250 (EQW00_00250) | - | 55554..57068 (-) | 1515 | WP_083553771.1 | class I SAM-dependent DNA methyltransferase | - |
| EQW00_RS00255 (EQW00_00255) | - | 57253..58227 (+) | 975 | WP_083553772.1 | nucleotidyltransferase | - |
| EQW00_RS00260 (EQW00_00260) | - | 58280..58768 (+) | 489 | WP_244307884.1 | hypothetical protein | - |
| EQW00_RS00265 (EQW00_00265) | - | 59153..59386 (-) | 234 | WP_002467980.1 | hypothetical protein | - |
| EQW00_RS00270 (EQW00_00270) | sesJ | 59626..62859 (+) | 3234 | WP_083043952.1 | MSCRAMM family cell wall-anchored protein SesJ | - |
| EQW00_RS00275 (EQW00_00275) | gtfA | 62948..64456 (+) | 1509 | WP_001551920.1 | accessory Sec system glycosyltransferase GtfA | - |
| EQW00_RS00280 (EQW00_00280) | gtfB | 64449..65768 (+) | 1320 | WP_001551922.1 | accessory Sec system glycosylation chaperone GtfB | - |
| EQW00_RS00285 (EQW00_00285) | - | 65949..66452 (-) | 504 | WP_001551924.1 | DUF1643 domain-containing protein | - |
| EQW00_RS00290 (EQW00_00290) | - | 66467..66781 (-) | 315 | WP_001551925.1 | DUF960 family protein | - |
| EQW00_RS00300 (EQW00_00300) | - | 66874..67215 (-) | 342 | WP_001551929.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| EQW00_RS00305 (EQW00_00305) | ccrB | 67739..69367 (-) | 1629 | WP_083553775.1 | recombinase family protein | Machinery gene |
| EQW00_RS00310 (EQW00_00310) | ccrA | 69389..70738 (-) | 1350 | WP_001551932.1 | recombinase family protein | Machinery gene |
| EQW00_RS00315 (EQW00_00315) | - | 70972..72765 (-) | 1794 | WP_002495148.1 | DUF927 domain-containing protein | - |
| EQW00_RS00320 (EQW00_00320) | - | 72765..73061 (-) | 297 | WP_000221967.1 | single-stranded DNA-binding protein | - |
| EQW00_RS00325 (EQW00_00325) | - | 73233..74816 (+) | 1584 | WP_001551935.1 | hypothetical protein | - |
| EQW00_RS00330 (EQW00_00330) | - | 74888..75820 (+) | 933 | WP_000364405.1 | hypothetical protein | - |
| EQW00_RS00335 (EQW00_00335) | - | 76246..76623 (+) | 378 | WP_000687965.1 | hypothetical protein | - |
| EQW00_RS00340 (EQW00_00340) | - | 77092..77589 (+) | 498 | WP_000051479.1 | hypothetical protein | - |
| EQW00_RS00345 (EQW00_00345) | - | 77845..77988 (+) | 144 | WP_001631028.1 | restriction endonuclease subunit R | - |
| EQW00_RS00350 (EQW00_00350) | - | 77981..79183 (+) | 1203 | WP_001631029.1 | restriction endonuclease subunit S | - |
| EQW00_RS00355 (EQW00_00355) | - | 79228..79444 (-) | 217 | Protein_65 | IS5/IS1182 family transposase | - |
| EQW00_RS00360 (EQW00_00360) | - | 79506..80003 (-) | 498 | WP_001631030.1 | GNAT family N-acetyltransferase | - |
| EQW00_RS00370 (EQW00_00370) | - | 80675..81085 (-) | 411 | WP_001631031.1 | DUF2871 domain-containing protein | - |
| EQW00_RS12275 | - | 81248..81468 (-) | 221 | Protein_68 | hypothetical protein | - |
| EQW00_RS00380 (EQW00_00380) | - | 81483..81986 (-) | 504 | WP_001631032.1 | DUF1643 domain-containing protein | - |
| EQW00_RS00385 (EQW00_00385) | - | 82002..82313 (-) | 312 | WP_001631033.1 | DUF960 domain-containing protein | - |
| EQW00_RS00390 (EQW00_00390) | - | 82400..82750 (-) | 351 | WP_001631034.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| EQW00_RS00395 (EQW00_00395) | ccrB | 83251..84879 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| EQW00_RS00400 (EQW00_00400) | ccrA | 84876..86237 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| EQW00_RS00405 (EQW00_00405) | - | 86424..87053 (-) | 630 | Protein_74 | hypothetical protein | - |
| EQW00_RS12280 | - | 87062..87400 (+) | 339 | Protein_75 | recombinase family protein | - |
| EQW00_RS00415 (EQW00_00415) | - | 87512..87871 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| EQW00_RS00420 (EQW00_00420) | - | 88078..88404 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EQW00_RS00430 (EQW00_00430) | - | 88734..90659 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| EQW00_RS00435 (EQW00_00435) | - | 91782..92732 (-) | 951 | Protein_79 | transposase | - |
| EQW00_RS00440 (EQW00_00440) | - | 92853..93422 (+) | 570 | WP_002470562.1 | hypothetical protein | - |
| EQW00_RS00445 (EQW00_00445) | - | 93467..94624 (+) | 1158 | WP_002485721.1 | hypothetical protein | - |
| EQW00_RS00450 (EQW00_00450) | - | 94807..95079 (+) | 273 | WP_002501902.1 | hypothetical protein | - |
| EQW00_RS00455 (EQW00_00455) | - | 95109..95783 (+) | 675 | WP_134943505.1 | IS6-like element IS257 family transposase | - |
| EQW00_RS00460 (EQW00_00460) | lspA | 95811..96263 (-) | 453 | WP_164071529.1 | signal peptidase II | - |
| EQW00_RS00465 (EQW00_00465) | - | 96423..96824 (+) | 402 | WP_057504659.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EQW00_RS00470 (EQW00_00470) | - | 97078..97845 (+) | 768 | WP_057504658.1 | ZIP family metal transporter | - |
| EQW00_RS00475 (EQW00_00475) | - | 98102..100510 (+) | 2409 | WP_002485759.1 | heavy metal translocating P-type ATPase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62474.71 Da Isoelectric Point: 9.6103
>NTDB_id=338933 EQW00_RS00395 WP_001631035.1 83251..84879(-) (ccrB) [Staphylococcus epidermidis strain ATCC 14990]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE
Nucleotide
Download Length: 1629 bp
>NTDB_id=338933 EQW00_RS00395 WP_001631035.1 83251..84879(-) (ccrB) [Staphylococcus epidermidis strain ATCC 14990]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
72.694 |
100 |
0.727 |