Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EQH16_RS02840 Genome accession   NZ_CP035264
Coordinates   534800..535537 (+) Length   245 a.a.
NCBI ID   WP_238090292.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901921     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 529800..540537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH16_RS02805 - 530730..530969 (-) 240 WP_001813906.1 hypothetical protein -
  EQH16_RS02810 (EQH16_02930) - 531131..531418 (-) 288 WP_000777760.1 hypothetical protein -
  EQH16_RS02815 (EQH16_02935) - 531428..531838 (-) 411 WP_001278301.1 HIT family protein -
  EQH16_RS02820 (EQH16_02940) pptA 531906..532637 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  EQH16_RS02825 (EQH16_02945) - 532634..533683 (+) 1050 WP_000653752.1 ABC transporter permease -
  EQH16_RS02830 (EQH16_02950) - 533851..534180 (-) 330 WP_000132572.1 hypothetical protein -
  EQH16_RS02835 (EQH16_02955) - 534457..534795 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  EQH16_RS02840 (EQH16_02960) comE/blpR 534800..535537 (+) 738 WP_238090292.1 response regulator transcription factor Regulator
  EQH16_RS02845 (EQH16_02965) - 535551..536891 (+) 1341 WP_001017622.1 sensor histidine kinase -
  EQH16_RS02850 (EQH16_02970) blpC 536933..537088 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  EQH16_RS02855 (EQH16_02975) - 537145..538506 (-) 1362 Protein_565 bacteriocin secretion accessory protein -
  EQH16_RS02860 (EQH16_02980) comA/nlmT 538517..540193 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28782.94 Da        Isoelectric Point: 6.2357

>NTDB_id=338602 EQH16_RS02840 WP_238090292.1 534800..535537(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901921]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSET
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=338602 EQH16_RS02840 WP_238090292.1 534800..535537(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901921]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTAGCTAGAAAGATTCGGGAACAAGAC
CCTTATGCCCTAATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCTCTGTCCTTTCGCTACCAAGTGTCAGCTTTGGA
CTACATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTCAAAGAGGTTTACTAT
CTCGAAACATCCCCAAGACCCCATCGTGTTATTCTCTATACCAAGACGGACAGGCTAGAATTTACGGCGAGTTTAGAGGA
GGTTTTTAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGACT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.909

99.184

0.535
  comE/comE1 Streptococcus equinus JB1

43.882

96.735

0.424
  comE/comE2 Streptococcus equinus JB1

38.843

98.776

0.384

Multiple sequence alignment