Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH24_RS09720 Genome accession   NZ_CP035256
Coordinates   1887720..1888544 (-) Length   274 a.a.
NCBI ID   WP_023396715.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1882720..1893544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS09715 (EQH24_10220) - 1886098..1887429 (-) 1332 WP_000390042.1 hemolysin family protein -
  EQH24_RS09720 (EQH24_10225) endA 1887720..1888544 (-) 825 WP_023396715.1 DNA-entry nuclease EndA Machinery gene
  EQH24_RS09725 (EQH24_10230) - 1888583..1888771 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  EQH24_RS09730 (EQH24_10235) murA 1888764..1890047 (-) 1284 WP_023396463.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH24_RS09735 (EQH24_10240) - 1890071..1890301 (-) 231 WP_000250391.1 DUF1146 family protein -
  EQH24_RS09740 (EQH24_10245) sepM 1890359..1891396 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  EQH24_RS09745 (EQH24_10250) coaD 1891380..1891868 (-) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  EQH24_RS09750 (EQH24_10255) rsmD 1891858..1892397 (-) 540 WP_000691938.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH24_RS09755 (EQH24_10260) asnA 1892462..1893454 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.62 Da        Isoelectric Point: 10.1197

>NTDB_id=338018 EQH24_RS09720 WP_023396715.1 1887720..1888544(-) (endA) [Streptococcus pneumoniae strain TVO_1901930]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=338018 EQH24_RS09720 WP_023396715.1 1887720..1888544(-) (endA) [Streptococcus pneumoniae strain TVO_1901930]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978

Multiple sequence alignment