Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EQH31_RS09385 Genome accession   NZ_CP035249
Coordinates   1828383..1829639 (-) Length   418 a.a.
NCBI ID   WP_000642703.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1823383..1834639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS09370 (EQH31_09940) - 1824612..1825964 (-) 1353 WP_000364180.1 MATE family efflux transporter -
  EQH31_RS09375 (EQH31_09950) - 1826020..1826834 (+) 815 Protein_1856 IS5-like element IS1515 family transposase -
  EQH31_RS09380 (EQH31_09960) recA 1827162..1828328 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  EQH31_RS09385 (EQH31_09965) cinA 1828383..1829639 (-) 1257 WP_000642703.1 competence/damage-inducible protein A Machinery gene
  EQH31_RS09390 (EQH31_09970) brpA 1829723..1830739 (-) 1017 WP_000239285.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH31_RS09395 (EQH31_09975) - 1830747..1831265 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  EQH31_RS09400 (EQH31_09980) tsaE 1831255..1831698 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH31_RS09405 (EQH31_09985) comM 1831784..1832404 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH31_RS09410 (EQH31_09995) - 1832787..1833557 (-) 771 WP_225415938.1 helix-turn-helix domain-containing protein -
  EQH31_RS09415 (EQH31_10000) - 1833839..1834009 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  EQH31_RS09420 (EQH31_10005) - 1834324..1834620 (+) 297 WP_000911559.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45046.49 Da        Isoelectric Point: 4.6027

>NTDB_id=337694 EQH31_RS09385 WP_000642703.1 1828383..1829639(-) (cinA) [Streptococcus pneumoniae strain TVO_1901938]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=337694 EQH31_RS09385 WP_000642703.1 1828383..1829639(-) (cinA) [Streptococcus pneumoniae strain TVO_1901938]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCTACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGGTCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAATTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.043

100

0.99
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment