Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH34_RS08835 Genome accession   NZ_CP035246
Coordinates   1757126..1757950 (-) Length   274 a.a.
NCBI ID   WP_001036783.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901941     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1752126..1762950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH34_RS08830 (EQH34_09365) - 1755504..1756835 (-) 1332 WP_000390042.1 hemolysin family protein -
  EQH34_RS08835 (EQH34_09370) endA 1757126..1757950 (-) 825 WP_001036783.1 DNA-entry nuclease EndA Machinery gene
  EQH34_RS08840 (EQH34_09375) - 1757989..1758177 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  EQH34_RS08845 (EQH34_09380) murA 1758170..1759453 (-) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH34_RS08850 (EQH34_09385) - 1759477..1759707 (-) 231 WP_000615437.1 DUF1146 family protein -
  EQH34_RS08855 (EQH34_09390) sepM 1759765..1760802 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  EQH34_RS08860 (EQH34_09395) coaD 1760786..1761274 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  EQH34_RS08865 (EQH34_09400) rsmD 1761264..1761803 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH34_RS08870 (EQH34_09405) asnA 1761868..1762860 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.66 Da        Isoelectric Point: 10.1700

>NTDB_id=337463 EQH34_RS08835 WP_001036783.1 1757126..1757950(-) (endA) [Streptococcus pneumoniae strain TVO_1901941]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=337463 EQH34_RS08835 WP_001036783.1 1757126..1757950(-) (endA) [Streptococcus pneumoniae strain TVO_1901941]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment