Detailed information NTG0336850

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: EQH43_RS09740
• Genome accession: NZ_CP035237
• Coordinates: 1903946..1904248 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_Taiwan19F-14
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1898946..1909248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH43_RS09710 (EQH43_10205)	rnpA	1899632..1900003 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH43_RS10865	-	1900020..1900151 (-)	132	WP_000768904.1	hypothetical protein	-
EQH43_RS09715 (EQH43_10210)	-	1900152..1901342 (-)	1191	WP_000167766.1	acetate kinase	-
EQH43_RS09720 (EQH43_10215)	comYH	1901393..1902346 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
EQH43_RS09725 (EQH43_10220)	-	1902407..1902994 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
EQH43_RS09730 (EQH43_10225)	comGG/cglG	1903131..1903544 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH43_RS09735 (EQH43_10230)	comGF/cglF	1903522..1903983 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH43_RS09740 (EQH43_10235)	comGE/cglE	1903946..1904248 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH43_RS09745 (EQH43_10240)	comGD/cglD	1904211..1904615 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH43_RS09750 (EQH43_10245)	comGC/cglC	1904608..1904934 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
EQH43_RS09755 (EQH43_10250)	comGB/cglB	1904936..1905952 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH43_RS09760 (EQH43_10255)	comGA/cglA/cilD	1905900..1906841 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH43_RS09765 (EQH43_10260)	-	1906917..1907282 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH43_RS09770 (EQH43_10265)	-	1907433..1908491 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=336850 EQH43_RS09740 WP_000413380.1 1903946..1904248(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=336850 EQH43_RS09740 WP_000413380.1 1903946..1904248(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39