Detailed information NTG0336649

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: FZC51_RS05470
• Genome accession: NZ_CP043389
• Coordinates: 1122488..1123261 (-)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain NRS384-rpoB-H481N-SCV
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1117488..1128261

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FZC51_RS05435 (FZC51_05435)	-	1117741..1118511 (-)	771	WP_000473705.1	isoprenyl transferase	-
FZC51_RS05440 (FZC51_05440)	frr	1118884..1119438 (-)	555	WP_001280006.1	ribosome recycling factor	-
FZC51_RS05445 (FZC51_05445)	pyrH	1119457..1120179 (-)	723	WP_000057330.1	UMP kinase	-
FZC51_RS05450 (FZC51_05450)	tsf	1120316..1121197 (-)	882	WP_000201387.1	translation elongation factor Ts	-
FZC51_RS05455 (FZC51_05455)	-	1121232..1121345 (-)	114	WP_001789890.1	hypothetical protein	-
FZC51_RS05460 (FZC51_05460)	rpsB	1121379..1122146 (-)	768	WP_000268484.1	30S ribosomal protein S2	-
FZC51_RS05465 (FZC51_05465)	-	1122345..1122437 (-)	93	WP_001790530.1	hypothetical protein	-
FZC51_RS05470 (FZC51_05470)	codY	1122488..1123261 (-)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
FZC51_RS05475 (FZC51_05475)	hslU	1123286..1124689 (-)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
FZC51_RS05480 (FZC51_05480)	hslV	1124755..1125300 (-)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
FZC51_RS05485 (FZC51_05485)	xerC	1125297..1126193 (-)	897	WP_001015597.1	tyrosine recombinase XerC	-
FZC51_RS05490 (FZC51_05490)	trmFO	1126610..1127917 (-)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=336649 FZC51_RS05470 WP_000055337.1 1122488..1123261(-) (codY) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=336649 FZC51_RS05470 WP_000055337.1 1122488..1123261(-) (codY) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428