Detailed information NTG0033359

Bioinformatically predicted

Overview

• Name: rcrP
• Type: Regulator
• Locus tag: SP70585_RS14045
• Genome accession: NC_012468
• Coordinates: 1842383..1843204 (-)
• Length: 273 a.a.
• NCBI ID: WP_000601682.1
• Uniprot ID: A0A4K3G7N8
• Organism: Streptococcus pneumoniae 70585
• Function: regulate competence (predicted from homology) Competence regulation

Genomic Context

Location: 1837383..1848204

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS09895 (SP70585_1992)	-	1837928..1838245 (-)	318	WP_000615767.1	thioredoxin family protein	-
SP70585_RS09900 (SP70585_1993)	-	1838242..1838541 (-)	300	WP_001013974.1	DUF4651 domain-containing protein	-
SP70585_RS14035	-	1838739..1838819 (-)	81	WP_223200442.1	hypothetical protein	-
SP70585_RS09905 (SP70585_1994)	-	1838826..1839017 (-)	192	WP_000291826.1	cell wall-binding protein	-
SP70585_RS09910 (SP70585_1995)	-	1839178..1839852 (-)	675	WP_000725719.1	LiaF transmembrane domain-containing protein	-
SP70585_RS09915 (SP70585_1996)	-	1839857..1840303 (-)	447	WP_000776596.1	LytTR family DNA-binding domain-containing protein	-
SP70585_RS09920 (SP70585_1997)	-	1840417..1840920 (-)	504	WP_000800945.1	phosphatase PAP2 family protein	-
SP70585_RS09925 (SP70585_1998)	-	1840917..1841279 (-)	363	WP_000078805.1	DUF2200 domain-containing protein	-
SP70585_RS14040 (SP70585_1999)	rcrQ	1841345..1842376 (-)	1032	WP_000506424.1	ABC transporter ATP-binding protein	Regulator
SP70585_RS14045 (SP70585_2000)	rcrP	1842383..1843204 (-)	822	WP_000601682.1	ABC transporter permease	Regulator
SP70585_RS09940 (SP70585_2001)	-	1843221..1843692 (-)	472	Protein_1883	MarR family winged helix-turn-helix transcriptional regulator	-
SP70585_RS09945 (SP70585_2002)	-	1843816..1844532 (-)	717	WP_000532876.1	YebC/PmpR family DNA-binding transcriptional regulator	-
SP70585_RS09950 (SP70585_2003)	ply	1845413..1846828 (-)	1416	WP_001284361.1	cholesterol-dependent cytolysin pneumolysin	-
SP70585_RS09955 (SP70585_2004)	-	1846839..1847249 (-)	411	WP_000595758.1	hypothetical protein	-
SP70585_RS09960 (SP70585_2005)	-	1847242..1847850 (-)	609	WP_000083614.1	hypothetical protein	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 30604.17 Da
• Isoelectric Point: 5.9310

>NTDB_id=33359 SP70585_RS14045 WP_000601682.1 1842383..1843204(-) (rcrP) [Streptococcus pneumoniae 70585]
MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPASMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDI
FNRVLDYSQTEIKKFSIPSLLTRTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNLFVNRLMAILNPIMMGISSGLSV
AIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM

Nucleotide

• Length: 822 bp

>NTDB_id=33359 SP70585_RS14045 WP_000601682.1 1842383..1843204(-) (rcrP) [Streptococcus pneumoniae 70585]
ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCGACCTATATCTCGAAAATTAC
GGATTTGCTAGGTAGTCAAGAAACTAATTTAGATGAGTTGTGGCAGCCGGCAAGCATGATGATGGGAATGTCCTTTCTTG
CCTTCTTGTCCGTAGTTGCAGTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTCTTGACGCGTACTACCAATGA
CATTACTCAAGTTCAAATGTTGATTACTATGGGCTTGCAAGTGGTAACGCGTGGTTCAATTATGGCTATCTGGGCTATTG
GGAAGATTTTAGGTCATTCAGAATACTGGCTCTGGGCCGTACTTGTGGTAGTGATTGTCAACGTCCTGATGACGACCGTT
TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGTTGACAGATAAACTGAACAGTATCACTCGTGAGAGTTT
AACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGATTATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGA
CCCGTTTGAATTTGTTTGTCAACCGTCTTATGGCTATTTTGAATCCTATCATGATGGGGATTTCAAGTGGTTTGAGTGTA
GCGATTTACTGGATTGGGGCCTATGTGATTAACGACGCTGCTCCGATAGCGCGTCTGCCTCTCTTTAGTGACATGATTAT
TTTCATGTCTTATGCCATGTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (3-271)

3D structure

• AlphaFold DB: A0A4K3G7N8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rcrP	Streptococcus mutans UA159	56.842	100	0.593