Detailed information NTG0331185

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PAKB6_RS24080
• Genome accession: NZ_CP034429
• Coordinates: 5082675..5084012 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain GIMC5015:PAKB6
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5077675..5089012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PAKB6_RS24055 (PAKB6_4748)	pgeF	5077818..5078546 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
PAKB6_RS24060 (PAKB6_4749)	rluD	5078543..5079505 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PAKB6_RS24065 (PAKB6_4750)	-	5079651..5080676 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PAKB6_RS24070 (PAKB6_4751)	-	5080833..5081078 (+)	246	WP_003102591.1	PP0621 family protein	-
PAKB6_RS24075 (PAKB6_4752)	pilS	5081068..5082660 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
PAKB6_RS24080 (PAKB6_4753)	pilR	5082675..5084012 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PAKB6_RS24085 (PAKB6_4754)	thiO	5084058..5085152 (-)	1095	WP_010895678.1	glycine oxidase ThiO	-
PAKB6_RS24090	-	5085287..5085796 (+)	510	WP_003112829.1	Tfp pilus assembly protein FimT/FimU	-
PAKB6_RS24095 (PAKB6_4755)	-	5085902..5086408 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
PAKB6_RS24100 (PAKB6_4756)	pilV	5086399..5086956 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PAKB6_RS24105 (PAKB6_4757)	pilW	5086953..5087777 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PAKB6_RS24110 (PAKB6_4758)	pilX	5087774..5088361 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=331185 PAKB6_RS24080 WP_003094694.1 5082675..5084012(+) (pilR) [Pseudomonas aeruginosa strain GIMC5015:PAKB6]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=331185 PAKB6_RS24080 WP_003094694.1 5082675..5084012(+) (pilR) [Pseudomonas aeruginosa strain GIMC5015:PAKB6]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384