Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   EFD74_RS04745 Genome accession   NZ_CP034259
Coordinates   992995..993564 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain P1D12C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 987995..998564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFD74_RS04725 (EFD74_04940) - 989500..990858 (+) 1359 WP_000021865.1 TrkH family potassium uptake protein -
  EFD74_RS04730 (EFD74_04945) - 990997..992508 (+) 1512 WP_000414165.1 bifunctional metallophosphatase/5'-nucleotidase -
  EFD74_RS04745 (EFD74_04960) comK/comK1 992995..993564 (-) 570 WP_000287265.1 competence protein ComK Regulator
  EFD74_RS04750 (EFD74_04965) - 993774..993992 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  EFD74_RS04755 (EFD74_04970) - 994073..995059 (-) 987 WP_156667997.1 lipoate--protein ligase -
  EFD74_RS04760 (EFD74_04975) - 995258..995434 (+) 177 WP_000214898.1 YkvS family protein -
  EFD74_RS04765 (EFD74_04980) - 995449..996051 (+) 603 WP_001033865.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  EFD74_RS14090 - 996366..996428 (+) 63 WP_228764722.1 hypothetical protein -
  EFD74_RS04775 (EFD74_04990) - 996967..997068 (+) 102 WP_001792055.1 hypothetical protein -
  EFD74_RS04780 (EFD74_04995) - 997078..997350 (+) 273 WP_001797239.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=330285 EFD74_RS04745 WP_000287265.1 992995..993564(-) (comK/comK1) [Staphylococcus aureus strain P1D12C1]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=330285 EFD74_RS04745 WP_000287265.1 992995..993564(-) (comK/comK1) [Staphylococcus aureus strain P1D12C1]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCTATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1

Multiple sequence alignment