Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   FP477_RS10465 Genome accession   NZ_CP042046
Coordinates   2030159..2032507 (+) Length   782 a.a.
NCBI ID   WP_001249290.1    Uniprot ID   -
Organism   Staphylococcus aureus strain B2-7A     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2025159..2037507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP477_RS10445 (FP477_10445) rnhC 2026268..2027206 (-) 939 WP_049307732.1 ribonuclease HIII -
  FP477_RS10450 (FP477_10450) zapA 2027576..2027835 (+) 260 Protein_1981 cell division protein ZapA -
  FP477_RS10455 (FP477_10455) - 2027843..2028364 (+) 522 WP_000234068.1 CvpA family protein -
  FP477_RS10460 (FP477_10460) polX 2028437..2030149 (+) 1713 WP_145377322.1 DNA polymerase/3'-5' exonuclease PolX -
  FP477_RS10465 (FP477_10465) mutS/mutS2 2030159..2032507 (+) 2349 WP_001249290.1 endonuclease MutS2 Machinery gene
  FP477_RS10470 (FP477_10470) trxA 2032680..2032994 (+) 315 WP_001018928.1 thioredoxin -
  FP477_RS10475 (FP477_10475) - 2033057..2033152 (-) 96 WP_001788625.1 hypothetical protein -
  FP477_RS10480 (FP477_10480) uvrC 2033318..2035099 (+) 1782 WP_000390529.1 excinuclease ABC subunit UvrC Machinery gene
  FP477_RS10485 (FP477_10485) - 2035423..2036037 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88656.22 Da        Isoelectric Point: 6.1086

>NTDB_id=330116 FP477_RS10465 WP_001249290.1 2030159..2032507(+) (mutS/mutS2) [Staphylococcus aureus strain B2-7A]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLEHNYKRVETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=330116 FP477_RS10465 WP_001249290.1 2030159..2032507(+) (mutS/mutS2) [Staphylococcus aureus strain B2-7A]
ATGAGACAAAAAACGTTAGACGTCTTAGAATTCGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATCTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTCAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATACCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACTGATC
TTTTTCAACAAATAAATGAAACATGCGATACGTATGATTTATATGATAATGCGAGTTATGAATTGCAAGGAATTAGAAGT
AAAATTTCGAGTACAAATCAACGTATTAGACAAAACTTAGATCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGACGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTGGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACAAGTCATGGGGCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTATTAAAGGAACAA
AGCCGATATTTAAAGAGGAACGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACTGTAACATTAAA
AACATTAGGTTTAATTATTGTTATGGCTCAATCAGGATTGTTGATTCCCACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAAATTTTAAAGCATGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCAAGTGAAGG
TGCTGCATTAGCAATGAGCATTTTAGATCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTATAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACTTTGAGTCCAACGTAT
AAGTTGTTAATGGGTGTGCCGGGTCGTTCAAATGCTTTTGATATTTCTAAAAAGTTAGGTCTTAGTTTGAATATTATTAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAATCATTAGAGCATAATTACAAACGTG
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAGTCTCTAATAGAGGAAGCGAAAGAAAAAGCAAATCAGAAGATTAAGGCTGCAACAAAAGA
AGCTGACGATATTATTAAAGACTTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AGAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTGTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTAGACTTACGAGGCTATCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCTGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGGTGGTATGCCAAGCGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(707-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

MutS domain V (MutS_V)

(332-512)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

49.937

100

0.504