Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   EGH12_RS07735 Genome accession   NZ_CP034020
Coordinates   1319527..1320189 (-) Length   220 a.a.
NCBI ID   WP_047916986.1    Uniprot ID   A0AA44U7R7
Organism   Neisseria gonorrhoeae strain FQ48     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1314527..1325189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH12_RS07700 (EGH12_07700) dut 1315156..1315608 (-) 453 WP_003701071.1 dUTP diphosphatase -
  EGH12_RS07705 (EGH12_07705) - 1315774..1316485 (+) 712 Protein_1329 AzlC family ABC transporter permease -
  EGH12_RS07710 (EGH12_07710) - 1316482..1316790 (+) 309 WP_003706588.1 AzlD family protein -
  EGH12_RS07715 (EGH12_07715) pilL 1316860..1317333 (-) 474 WP_012503482.1 PilX family type IV pilin Machinery gene
  EGH12_RS07720 (EGH12_07720) pilK 1317335..1317943 (-) 609 WP_047921847.1 pilus assembly protein Machinery gene
  EGH12_RS07725 (EGH12_07725) pilJ 1317922..1318884 (-) 963 WP_047921846.1 PilW family protein Machinery gene
  EGH12_RS07730 (EGH12_07730) pilI 1318881..1319495 (-) 615 WP_012503479.1 type IV pilus modification protein PilV Machinery gene
  EGH12_RS07735 (EGH12_07735) pilH 1319527..1320189 (-) 663 WP_047916986.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  EGH12_RS07740 (EGH12_07740) dnaB 1320446..1321849 (-) 1404 WP_012503477.1 replicative DNA helicase -
  EGH12_RS07750 (EGH12_07750) - 1322013..1322594 (+) 582 WP_003690895.1 superoxide dismutase -
  EGH12_RS07760 (EGH12_07760) - 1322826..1323335 (-) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  EGH12_RS07765 (EGH12_07765) - 1323665..1323997 (-) 333 WP_003687908.1 hypothetical protein -
  EGH12_RS07770 (EGH12_07770) cysT 1324183..1325012 (+) 830 Protein_1340 sulfate ABC transporter permease subunit CysT -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24557.00 Da        Isoelectric Point: 9.6166

>NTDB_id=328147 EGH12_RS07735 WP_047916986.1 1319527..1320189(-) (pilH) [Neisseria gonorrhoeae strain FQ48]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNFKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH

Nucleotide


Download         Length: 663 bp        

>NTDB_id=328147 EGH12_RS07735 WP_047916986.1 1319527..1320189(-) (pilH) [Neisseria gonorrhoeae strain FQ48]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTTCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

95.455

100

0.955

Multiple sequence alignment