Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   FDP16_RS11455 Genome accession   NZ_CP040798
Coordinates   2290606..2292429 (-) Length   607 a.a.
NCBI ID   WP_105025991.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain CGMH058     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2285606..2297429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS11430 (FDP16_11910) - 2287212..2287463 (-) 252 WP_176799714.1 hypothetical protein -
  FDP16_RS11435 (FDP16_11915) - 2287740..2288204 (-) 465 WP_176799715.1 single-stranded DNA-binding protein -
  FDP16_RS11440 (FDP16_11920) - 2288220..2289041 (-) 822 WP_176799716.1 LPXTG cell wall anchor domain-containing protein -
  FDP16_RS11445 (FDP16_11925) - 2289062..2290144 (-) 1083 WP_176799717.1 hypothetical protein -
  FDP16_RS11450 (FDP16_11930) - 2290162..2290509 (-) 348 WP_053794437.1 TrbC/VirB2 family protein -
  FDP16_RS11455 (FDP16_11935) clpE 2290606..2292429 (-) 1824 WP_105025991.1 AAA family ATPase Regulator
  FDP16_RS11460 (FDP16_11940) - 2292423..2294180 (-) 1758 WP_176799718.1 type IA DNA topoisomerase -

Sequence

Protein


Download         Length: 607 a.a.        Molecular weight: 67921.64 Da        Isoelectric Point: 5.0120

>NTDB_id=323359 FDP16_RS11455 WP_105025991.1 2290606..2292429(-) (clpE) [Streptococcus sanguinis strain CGMH058]
MVKTPFLEKYTDNLSAKIAKKEADYEVYGRDEEIQNVITSLRRRTKNNPILVGEAGVGKTAIVEGLALAILRDQVPNDLK
GLTVRSLELSSLMSGDDGGFIPKFKNIIQEMIATKGQNILFVDEFHTIVGAGSQNGESLDAGNIIKPALARGELQLIGAT
TLDEFHDYVETDRALERRVQKVMVEEPTIPEAITIIDQAKVIYEDFHRIKISRAAVETAVRLSVRYITDRFLPDKAFDLI
DEAATISSAENKELVTEKEIAQVLKNKTGIPITTILKGDNERLAGFKEKLLKRVKGQDEAIDAVVDAVTIAQAGLQDENK
PISSFLFLGPTGVGKTELSKAVAEALFDDEDAMLRFDMSEYKQKEDVAKLIGNRGTRTKGQLTEGVKQKPYCVLLLDEIE
KADGEVLDLFLQVLDDGRLTDATGRLVSFKNTIVIMTTNVGAKKIIDKAELKGNFKNLTDRERQQFERSMENVLQREFRP
EYLNRIENKLIFNLLESDVIEEIAEKNLSEIALRMKRQNLTLSYDSSLIAYLSDVGTDVRNGARPLERLIKRKVLAPISA
KSLDLNKTTQSYNIHVWVEGEAPDGSHRVDQRQLHFDVTEPLEVLFS

Nucleotide


Download         Length: 1824 bp        

>NTDB_id=323359 FDP16_RS11455 WP_105025991.1 2290606..2292429(-) (clpE) [Streptococcus sanguinis strain CGMH058]
ATGGTGAAAACTCCATTTTTGGAAAAATACACGGATAACTTATCGGCTAAAATTGCTAAAAAAGAAGCAGATTATGAGGT
TTACGGACGAGATGAGGAAATCCAGAACGTCATTACTTCTCTTCGCAGGCGCACTAAAAATAACCCAATTCTGGTTGGAG
AAGCGGGCGTTGGGAAGACTGCTATTGTAGAAGGGCTTGCTTTAGCCATTTTAAGAGATCAGGTGCCAAATGATCTAAAA
GGCTTAACTGTCCGCTCTTTGGAGCTCTCCAGTCTAATGAGTGGTGACGACGGTGGTTTTATTCCTAAATTTAAAAACAT
CATTCAAGAAATGATTGCTACCAAAGGCCAAAATATCCTTTTTGTCGATGAATTTCATACTATTGTTGGGGCGGGAAGCC
AAAACGGGGAGTCTCTTGACGCTGGAAATATTATCAAGCCAGCCCTAGCACGTGGGGAGCTCCAGCTAATTGGGGCTACC
ACATTAGACGAATTTCACGACTACGTGGAAACAGACCGAGCCTTGGAACGGCGGGTTCAAAAAGTTATGGTTGAAGAACC
GACAATTCCTGAAGCGATCACAATTATTGATCAAGCTAAGGTAATCTATGAAGACTTTCATCGCATCAAAATTAGTCGAG
CTGCCGTAGAAACGGCAGTCAGGCTCTCAGTTCGTTATATTACAGACCGCTTCCTGCCTGACAAGGCCTTTGATCTGATT
GACGAGGCTGCCACTATTTCCTCAGCCGAAAACAAAGAGCTGGTCACCGAAAAAGAAATTGCCCAAGTCTTGAAGAATAA
GACGGGGATCCCGATTACCACCATTCTAAAAGGTGATAATGAACGCCTAGCTGGCTTTAAAGAAAAGCTATTGAAACGGG
TCAAAGGCCAAGATGAAGCTATTGACGCTGTGGTAGATGCTGTTACGATTGCTCAAGCAGGGCTTCAGGATGAAAATAAA
CCAATTTCATCTTTCCTTTTTCTTGGCCCAACAGGAGTCGGAAAAACTGAATTATCAAAAGCAGTGGCGGAGGCACTTTT
TGATGATGAAGATGCCATGCTGCGCTTTGATATGTCTGAATATAAACAGAAGGAAGACGTTGCCAAACTGATTGGTAATA
GAGGAACCAGGACAAAGGGCCAGCTGACTGAAGGAGTCAAACAGAAACCTTACTGTGTGCTATTGCTGGATGAAATTGAA
AAGGCGGATGGTGAGGTGCTTGATCTCTTCTTGCAGGTCTTAGATGATGGTCGTCTGACAGATGCCACAGGCCGCCTTGT
GAGTTTTAAAAATACGATTGTGATTATGACGACAAACGTTGGAGCGAAGAAAATCATTGATAAGGCGGAGCTGAAAGGCA
ACTTTAAAAATCTGACAGATCGGGAACGCCAACAGTTTGAACGCAGTATGGAAAATGTACTCCAGAGAGAGTTCCGACCT
GAATATCTAAATCGTATTGAAAATAAACTGATTTTCAATCTGCTGGAAAGTGATGTTATTGAAGAAATTGCGGAGAAAAA
TCTATCAGAGATTGCGTTGCGGATGAAACGCCAAAATCTCACTCTATCCTATGACTCTAGCTTGATTGCTTATTTATCCG
ACGTGGGAACAGATGTTAGAAATGGGGCCCGTCCACTGGAACGTTTGATTAAGCGGAAAGTCTTGGCTCCTATTTCTGCT
AAAAGCCTAGACCTCAATAAAACGACTCAATCTTACAATATCCATGTTTGGGTAGAGGGCGAGGCTCCAGATGGCAGTCA
CCGTGTCGATCAGCGCCAACTTCATTTTGATGTGACAGAGCCCCTGGAAGTTCTCTTCAGTTGA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(495-564)

AAA lid domain (AAA_lid_9)

(189-262)

ATPase family associated with various cellular activities (AAA) (AAA)

(50-162)

AAA domain (Cdc48 subfamily) (AAA_2)

(320-487)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

42.763

100

0.428
  clpE Streptococcus pneumoniae R6

42.81

99.671

0.427
  clpE Streptococcus pneumoniae D39

42.81

99.671

0.427
  clpE Streptococcus pneumoniae Rx1

42.81

99.671

0.427
  clpE Streptococcus pneumoniae TIGR4

42.81

99.671

0.427
  clpC Lactococcus lactis subsp. cremoris KW2

41.776

100

0.418
  clpC Streptococcus thermophilus LMD-9

42.301

97.364

0.412
  clpC Streptococcus pneumoniae D39

41.528

99.176

0.412
  clpC Streptococcus pneumoniae Rx1

41.528

99.176

0.412
  clpC Streptococcus pneumoniae TIGR4

41.528

99.176

0.412
  clpC Streptococcus thermophilus LMG 18311

42.132

97.364

0.41
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

40

100

0.405
  clpC Streptococcus mutans UA159

40.63

94.069

0.382