Detailed information NTG0320306

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FD482_RS05800
• Genome accession: NZ_CP040229
• Coordinates: 1227180..1229798 (+)
• Length: 872 a.a.
• NCBI ID: WP_000073346.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain GD487
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1222180..1234798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD482_RS05775 (FD482_05970)	-	1223036..1223983 (+)	948	WP_000121214.1	IS30-like element ISSau1 family transposase	-
FD482_RS05780 (FD482_05975)	-	1224022..1224315 (+)	294	WP_000655666.1	MTH1187 family thiamine-binding protein	-
FD482_RS05785 (FD482_05980)	miaB	1224449..1225993 (+)	1545	WP_001001522.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
FD482_RS05790 (FD482_05985)	-	1225994..1226359 (+)	366	WP_000282384.1	RicAFT regulatory complex protein RicA family protein	-
FD482_RS05795 (FD482_05990)	thiW	1226386..1226877 (+)	492	WP_000842283.1	energy coupling factor transporter S component ThiW	-
FD482_RS05800 (FD482_05995)	hexA	1227180..1229798 (+)	2619	WP_000073346.1	DNA mismatch repair protein MutS	Machinery gene
FD482_RS05805 (FD482_06000)	hexB	1229811..1231820 (+)	2010	WP_000516257.1	DNA mismatch repair endonuclease MutL	Machinery gene
FD482_RS05810 (FD482_06005)	-	1231826..1232368 (+)	543	WP_001072706.1	glycerol-3-phosphate responsive antiterminator	-
FD482_RS05815 (FD482_06010)	-	1232843..1233661 (+)	819	WP_138766965.1	MIP/aquaporin family protein	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99945.68 Da
• Isoelectric Point: 4.6322

>NTDB_id=320306 FD482_RS05800 WP_000073346.1 1227180..1229798(+) (hexA) [Staphylococcus aureus strain GD487]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDHLKRQINMVTETITVRETLSTEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQDTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNMQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENSNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=320306 FD482_RS05800 WP_000073346.1 1227180..1229798(+) (hexA) [Staphylococcus aureus strain GD487]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGTGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATCATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCAACAGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCAAAAAAAGGAACGCTACTTTGGCTAATGGACGAAACGAAAACACCAATGGGAGCACGCCGCTTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAGATACCAAATATTAAAGCATTACTAAATTCTATGAATCAGGATA
CTCTTGTACAAGTTAATCAACTGGAGCCACTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGTGGACTATTCAAAGTTGGTTTTAATATGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAATTACAAGCCAAAGAAAGACAACGTACTGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCGGAACGATTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATTGAATTAGAATATCAATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGTTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTATACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCTGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAACGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACGTATATGAGAC
AAGTTGCCATAATTAGTATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCTGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCACATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATCCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTCAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (5-115)

• MutS domain II (MutS_II) (125-237)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (412-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.455	100	0.459