Detailed information NTG0319408

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: D9C12_RS10665
• Genome accession: NZ_CP032857
• Coordinates: 2031312..2032091 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis subsp. subtilis strain 2RL2-3
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 2026312..2037091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D9C12_RS10645 (D9C12_10645)	trmFO	2027005..2028312 (+)	1308	WP_069837510.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
D9C12_RS10650 (D9C12_10650)	xerC	2028380..2029294 (+)	915	WP_014479777.1	tyrosine recombinase XerC	-
D9C12_RS10655 (D9C12_10655)	clpQ	2029307..2029852 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
D9C12_RS10660 (D9C12_10660)	hslU	2029869..2031272 (+)	1404	WP_014476801.1	HslU--HslV peptidase ATPase subunit	-
D9C12_RS10665 (D9C12_10665)	codY	2031312..2032091 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
D9C12_RS10670 (D9C12_10670)	flgB	2032471..2032860 (+)	390	WP_014479778.1	flagellar basal body rod protein FlgB	-
D9C12_RS10675 (D9C12_10675)	flgC	2032860..2033312 (+)	453	WP_014479779.1	flagellar basal body rod protein FlgC	-
D9C12_RS10680 (D9C12_10680)	fliE	2033323..2033643 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
D9C12_RS10685 (D9C12_10685)	fliF	2033689..2035299 (+)	1611	WP_046160402.1	flagellar basal-body MS-ring/collar protein FliF	-
D9C12_RS10690 (D9C12_10690)	fliG	2035312..2036328 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
D9C12_RS10695 (D9C12_10695)	fliH	2036321..2037073 (+)	753	WP_014479782.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=319408 D9C12_RS10665 WP_003220850.1 2031312..2032091(+) (codY) [Bacillus subtilis subsp. subtilis strain 2RL2-3]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=319408 D9C12_RS10665 WP_003220850.1 2031312..2032091(+) (codY) [Bacillus subtilis subsp. subtilis strain 2RL2-3]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCTATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCTTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467