Detailed information NTG0314620

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: AM490_RS10335
• Genome accession: NZ_CP032257
• Coordinates: 1983990..1985327 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain AR_0111
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1978990..1990327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AM490_RS10310 (AM490_10310)	pgeF	1979133..1979861 (-)	729	WP_003161770.1	peptidoglycan editing factor PgeF	-
AM490_RS10315 (AM490_10315)	rluD	1979858..1980820 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
AM490_RS10320 (AM490_10320)	-	1980966..1981991 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
AM490_RS10325 (AM490_10325)	-	1982148..1982393 (+)	246	WP_003102591.1	PP0621 family protein	-
AM490_RS10330 (AM490_10330)	pilS	1982383..1983975 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
AM490_RS10335 (AM490_10335)	pilR	1983990..1985327 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
AM490_RS10340 (AM490_10340)	thiO	1985373..1986467 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
AM490_RS10345 (AM490_10345)	-	1986602..1987111 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
AM490_RS10350 (AM490_10350)	-	1987217..1987723 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
AM490_RS10355 (AM490_10355)	pilV	1987714..1988271 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
AM490_RS10360 (AM490_10360)	pilW	1988268..1989092 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
AM490_RS10365 (AM490_10365)	pilX	1989089..1989676 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=314620 AM490_RS10335 WP_003094694.1 1983990..1985327(+) (pilR) [Pseudomonas aeruginosa strain AR_0111]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=314620 AM490_RS10335 WP_003094694.1 1983990..1985327(+) (pilR) [Pseudomonas aeruginosa strain AR_0111]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384