Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DY470_RS19225 Genome accession   NZ_CP031642
Coordinates   3656293..3657072 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus anthracis strain MCCC 1A02161     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3621969..3695899 3656293..3657072 within 0


Gene organization within MGE regions


Location: 3621969..3695899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DY470_RS19070 (DY470_19070) - 3622312..3623982 (-) 1671 WP_000823085.1 ribonuclease J -
  DY470_RS19080 (DY470_19080) dapA 3624749..3625627 (-) 879 WP_000564761.1 4-hydroxy-tetrahydrodipicolinate synthase -
  DY470_RS19085 (DY470_19085) dapG 3625639..3626871 (-) 1233 WP_071736929.1 aspartate kinase -
  DY470_RS19090 (DY470_19090) asd 3626895..3627941 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  DY470_RS19095 (DY470_19095) dpaB 3628092..3628691 (-) 600 WP_071736928.1 dipicolinate synthase subunit B -
  DY470_RS19100 (DY470_19100) dpaA 3628688..3629590 (-) 903 WP_000954724.1 dipicolinic acid synthetase subunit A -
  DY470_RS19105 (DY470_19105) - 3629865..3630116 (-) 252 WP_001239747.1 YlmC/YmxH family sporulation protein -
  DY470_RS19110 (DY470_19110) - 3630243..3631484 (-) 1242 WP_000592994.1 pitrilysin family protein -
  DY470_RS19115 (DY470_19115) - 3631571..3632470 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  DY470_RS19120 (DY470_19120) pnp 3632622..3634760 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  DY470_RS19125 (DY470_19125) rpsO 3634921..3635190 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  DY470_RS19130 (DY470_19130) ribF 3635291..3636262 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  DY470_RS19135 (DY470_19135) truB 3636306..3637229 (-) 924 WP_071736927.1 tRNA pseudouridine(55) synthase TruB -
  DY470_RS19140 (DY470_19140) rbfA 3637316..3637672 (-) 357 WP_000776442.1 30S ribosome-binding factor RbfA -
  DY470_RS19145 (DY470_19145) - 3637688..3637969 (-) 282 WP_000582364.1 DUF503 family protein -
  DY470_RS19150 (DY470_19150) infB 3637966..3640026 (-) 2061 WP_000036341.1 translation initiation factor IF-2 -
  DY470_RS19155 (DY470_19155) - 3640031..3640342 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  DY470_RS19160 (DY470_19160) - 3640343..3640615 (-) 273 WP_071736926.1 YlxR family protein -
  DY470_RS19165 (DY470_19165) nusA 3640627..3641733 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  DY470_RS19170 (DY470_19170) rimP 3641751..3642221 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  DY470_RS19175 (DY470_19175) - 3642554..3646855 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  DY470_RS19180 (DY470_19180) - 3646980..3648680 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  DY470_RS19185 (DY470_19185) rseP 3648790..3650046 (-) 1257 WP_001090229.1 RIP metalloprotease RseP -
  DY470_RS19190 (DY470_19190) dxr 3650063..3651205 (-) 1143 WP_071736925.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  DY470_RS19195 (DY470_19195) cdsA 3651229..3652020 (-) 792 WP_000813583.1 phosphatidate cytidylyltransferase -
  DY470_RS19200 (DY470_19200) uppS 3652038..3652814 (-) 777 WP_000971301.1 isoprenyl transferase -
  DY470_RS19205 (DY470_19205) frr 3652900..3653457 (-) 558 WP_000531503.1 ribosome recycling factor -
  DY470_RS19210 (DY470_19210) pyrH 3653460..3654182 (-) 723 WP_071736924.1 UMP kinase -
  DY470_RS19215 (DY470_19215) tsf 3654249..3655136 (-) 888 WP_001018581.1 translation elongation factor Ts -
  DY470_RS19220 (DY470_19220) rpsB 3655240..3655941 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  DY470_RS19225 (DY470_19225) codY 3656293..3657072 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DY470_RS19230 (DY470_19230) hslU 3657150..3658541 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  DY470_RS19235 (DY470_19235) hslV 3658564..3659106 (-) 543 WP_000526271.1 ATP-dependent protease proteolytic subunit HslV -
  DY470_RS19240 (DY470_19240) xerC 3659149..3660048 (-) 900 WP_071736923.1 tyrosine recombinase XerC -
  DY470_RS19245 (DY470_19245) trmFO 3660114..3661418 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  DY470_RS19250 (DY470_19250) topA 3661469..3663547 (-) 2079 WP_001286967.1 type I DNA topoisomerase -
  DY470_RS19255 (DY470_19255) dprA 3663692..3664561 (-) 870 WP_000818033.1 DNA-processing protein DprA -
  DY470_RS19260 (DY470_19260) sucD 3664649..3665551 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  DY470_RS19265 (DY470_19265) sucC 3665571..3666731 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  DY470_RS19270 (DY470_19270) rnhB 3666925..3667698 (-) 774 WP_071736922.1 ribonuclease HII -
  DY470_RS19275 (DY470_19275) ylqF 3667750..3668640 (-) 891 WP_000236696.1 ribosome biogenesis GTPase YlqF -
  DY470_RS19280 (DY470_19280) lepB 3668661..3669212 (-) 552 WP_000711857.1 signal peptidase I -
  DY470_RS19285 (DY470_19285) rplS 3669314..3669658 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  DY470_RS19290 (DY470_19290) trmD 3669805..3670539 (-) 735 WP_062923032.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DY470_RS19295 (DY470_19295) rimM 3670539..3671054 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  DY470_RS19300 (DY470_19300) - 3671175..3671402 (-) 228 WP_000737398.1 KH domain-containing protein -
  DY470_RS19305 (DY470_19305) rpsP 3671417..3671689 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  DY470_RS19310 (DY470_19310) ffh 3671790..3673139 (-) 1350 WP_000863461.1 signal recognition particle protein -
  DY470_RS19315 (DY470_19315) - 3673152..3673484 (-) 333 WP_000891062.1 putative DNA-binding protein -
  DY470_RS19320 (DY470_19320) ftsY 3673619..3674608 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  DY470_RS19325 (DY470_19325) smc 3674624..3678193 (-) 3570 WP_071736921.1 chromosome segregation protein SMC -
  DY470_RS19330 (DY470_19330) rncS 3678340..3679077 (-) 738 WP_001146873.1 ribonuclease III -
  DY470_RS19335 (DY470_19335) acpP 3679136..3679369 (-) 234 WP_000786062.1 acyl carrier protein -
  DY470_RS19340 (DY470_19340) fabG 3679439..3680179 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  DY470_RS19345 (DY470_19345) fabD 3680179..3681123 (-) 945 WP_071736920.1 ACP S-malonyltransferase -
  DY470_RS19350 (DY470_19350) plsX 3681138..3682130 (-) 993 WP_071736919.1 phosphate acyltransferase PlsX -
  DY470_RS19355 (DY470_19355) fapR 3682127..3682720 (-) 594 WP_000747352.1 transcription factor FapR -
  DY470_RS19360 (DY470_19360) recG 3682809..3684857 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  DY470_RS19365 (DY470_19365) - 3685147..3686823 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  DY470_RS19370 (DY470_19370) - 3686846..3687208 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  DY470_RS19375 (DY470_19375) rpmB 3687587..3687775 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  DY470_RS19380 (DY470_19380) spoVM 3687849..3687929 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  DY470_RS19385 (DY470_19385) - 3687996..3688676 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  DY470_RS19390 (DY470_19390) rpe 3688776..3689420 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  DY470_RS19395 (DY470_19395) rsgA 3689423..3690304 (-) 882 WP_071736918.1 ribosome small subunit-dependent GTPase A -
  DY470_RS19400 (DY470_19400) prkC 3690575..3692548 (-) 1974 WP_000904761.1 serine/threonine protein kinase PrkC -
  DY470_RS19405 (DY470_19405) - 3692557..3693309 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DY470_RS19410 (DY470_19410) rlmN 3693314..3694402 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  DY470_RS19415 (DY470_19415) rsmB 3694407..3695741 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=309294 DY470_RS19225 WP_000421288.1 3656293..3657072(-) (codY) [Bacillus anthracis strain MCCC 1A02161]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=309294 DY470_RS19225 WP_000421288.1 3656293..3657072(-) (codY) [Bacillus anthracis strain MCCC 1A02161]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment