Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EXA24_RS04025 Genome accession   NZ_CP036376
Coordinates   739731..740516 (+) Length   261 a.a.
NCBI ID   WP_000825431.1    Uniprot ID   Q8E0P2
Organism   Streptococcus agalactiae strain Sag153     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 734731..745516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA24_RS03995 (EXA24_04130) - 735848..736291 (+) 444 WP_001048166.1 hypothetical protein -
  EXA24_RS04000 (EXA24_04135) - 736376..736642 (+) 267 WP_001865676.1 hypothetical protein -
  EXA24_RS04005 (EXA24_04140) - 736743..736871 (+) 129 WP_000962057.1 hypothetical protein -
  EXA24_RS04010 (EXA24_04145) - 736880..737200 (+) 321 WP_001865677.1 hypothetical protein -
  EXA24_RS04015 (EXA24_04150) - 737297..737968 (+) 672 WP_000891267.1 ABC transporter ATP-binding protein -
  EXA24_RS04020 (EXA24_04155) - 738025..739470 (-) 1446 WP_000750932.1 FAD/NAD(P)-binding protein -
  EXA24_RS04025 (EXA24_04160) endA 739731..740516 (+) 786 WP_000825431.1 DNA/RNA non-specific endonuclease Machinery gene
  EXA24_RS04030 (EXA24_04165) - 740594..741232 (-) 639 WP_000478529.1 VTT domain-containing protein -
  EXA24_RS04035 (EXA24_04170) - 741449..742105 (+) 657 WP_000121095.1 ATP-binding cassette domain-containing protein -
  EXA24_RS04040 (EXA24_04175) fetB 742102..742875 (+) 774 WP_000011926.1 iron export ABC transporter permease subunit FetB -
  EXA24_RS04045 (EXA24_04180) - 743039..743857 (+) 819 WP_000601007.1 hypothetical protein -
  EXA24_RS04050 (EXA24_04185) - 743894..744778 (-) 885 WP_000354840.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 29424.86 Da        Isoelectric Point: 8.9989

>NTDB_id=307002 EXA24_RS04025 WP_000825431.1 739731..740516(+) (endA) [Streptococcus agalactiae strain Sag153]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=307002 EXA24_RS04025 WP_000825431.1 739731..740516(+) (endA) [Streptococcus agalactiae strain Sag153]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(77-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

51.515

75.862

0.391
  endA Streptococcus pneumoniae D39

51.515

75.862

0.391
  endA Streptococcus pneumoniae R6

51.515

75.862

0.391
  endA Streptococcus pneumoniae TIGR4

51.515

75.862

0.391

Multiple sequence alignment