Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DK237_RS06020 Genome accession   NZ_CP031377
Coordinates   1179135..1179974 (-) Length   279 a.a.
NCBI ID   WP_002936004.1    Uniprot ID   A0A126UN93
Organism   Streptococcus suis strain ISU2614     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1174135..1184974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS06005 (DK237_06165) uidA 1174496..1176295 (-) 1800 WP_002938035.1 beta-glucuronidase -
  DK237_RS06010 (DK237_06170) - 1176311..1177339 (-) 1029 WP_013730404.1 sugar kinase -
  DK237_RS06015 (DK237_06175) - 1177395..1178948 (-) 1554 WP_013730405.1 MFS transporter -
  DK237_RS06020 (DK237_06180) endA 1179135..1179974 (-) 840 WP_002936004.1 DNA/RNA non-specific endonuclease Machinery gene
  DK237_RS06025 (DK237_06185) - 1180004..1180195 (-) 192 WP_002936005.1 DNA-directed RNA polymerase subunit beta -
  DK237_RS06030 (DK237_06190) murA 1180188..1181477 (-) 1290 WP_024415642.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DK237_RS06035 (DK237_06195) - 1181502..1181726 (-) 225 WP_024387485.1 DUF1146 family protein -
  DK237_RS06040 (DK237_06200) - 1181786..1182202 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  DK237_RS06045 (DK237_06205) atpD 1182212..1183618 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  DK237_RS06050 (DK237_06210) - 1183638..1184516 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30175.36 Da        Isoelectric Point: 6.2370

>NTDB_id=306344 DK237_RS06020 WP_002936004.1 1179135..1179974(-) (endA) [Streptococcus suis strain ISU2614]
MAKKNVRKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRIRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=306344 DK237_RS06020 WP_002936004.1 1179135..1179974(-) (endA) [Streptococcus suis strain ISU2614]
ATGGCGAAGAAAAATGTAAGAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTCGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACAGATTTAGATGCATCGGTTGCCAGTGTACCTTATGGTGATAATAAGACAAA
GACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTATCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UN93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.915

84.588

0.591
  endA Streptococcus pneumoniae D39

69.915

84.588

0.591
  endA Streptococcus pneumoniae R6

69.915

84.588

0.591
  endA Streptococcus pneumoniae TIGR4

69.915

84.588

0.591

Multiple sequence alignment