Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EWG56_RS01975 Genome accession   NZ_CP035671
Coordinates   385641..386414 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain VB31683     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 380641..391414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EWG56_RS01940 (EWG56_01940) - 380894..381664 (-) 771 WP_000473699.1 isoprenyl transferase -
  EWG56_RS01945 (EWG56_01945) frr 382037..382591 (-) 555 WP_001280006.1 ribosome recycling factor -
  EWG56_RS01950 (EWG56_01950) pyrH 382610..383332 (-) 723 WP_000057330.1 UMP kinase -
  EWG56_RS01955 (EWG56_01955) tsf 383469..384350 (-) 882 WP_000201387.1 translation elongation factor Ts -
  EWG56_RS01960 (EWG56_01960) - 384385..384498 (-) 114 WP_001789890.1 hypothetical protein -
  EWG56_RS01965 (EWG56_01965) rpsB 384532..385299 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  EWG56_RS01970 (EWG56_01970) - 385498..385590 (-) 93 WP_031788481.1 hypothetical protein -
  EWG56_RS01975 (EWG56_01975) codY 385641..386414 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EWG56_RS01980 (EWG56_01980) hslU 386439..387842 (-) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  EWG56_RS01985 (EWG56_01985) hslV 387908..388453 (-) 546 WP_000072678.1 ATP-dependent protease subunit HslV -
  EWG56_RS01990 (EWG56_01990) xerC 388450..389346 (-) 897 WP_001015609.1 tyrosine recombinase XerC -
  EWG56_RS01995 (EWG56_01995) trmFO 389726..391069 (-) 1344 WP_000195253.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=304131 EWG56_RS01975 WP_000055337.1 385641..386414(-) (codY) [Staphylococcus aureus strain VB31683]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=304131 EWG56_RS01975 WP_000055337.1 385641..386414(-) (codY) [Staphylococcus aureus strain VB31683]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428