Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT44_RS02225 Genome accession   NZ_CP035455
Coordinates   411003..411785 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain emm197     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 406003..416785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT44_RS02205 (ETT44_02205) - 406341..407306 (-) 966 WP_002992573.1 asparaginase -
  ETT44_RS02210 (ETT44_02210) - 407378..408766 (+) 1389 WP_063632405.1 Cof-type HAD-IIB family hydrolase -
  ETT44_RS02215 (ETT44_02215) - 408888..409340 (-) 453 WP_002992571.1 universal stress protein -
  ETT44_RS02220 (ETT44_02220) - 409571..410785 (+) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  ETT44_RS02225 (ETT44_02225) codY 411003..411785 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT44_RS02230 (ETT44_02230) - 411932..412486 (+) 555 WP_002992568.1 cysteine hydrolase family protein -
  ETT44_RS02240 (ETT44_02240) - 413024..413248 (+) 225 WP_247580026.1 putative PEP-binding protein -
  ETT44_RS02245 (ETT44_02245) gatC 413480..413782 (+) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT44_RS02250 (ETT44_02250) gatA 413782..415248 (+) 1467 WP_023605256.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT44_RS02255 (ETT44_02255) gatB 415248..416687 (+) 1440 WP_136021949.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=303544 ETT44_RS02225 WP_002983278.1 411003..411785(+) (codY) [Streptococcus pyogenes strain emm197]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=303544 ETT44_RS02225 WP_002983278.1 411003..411785(+) (codY) [Streptococcus pyogenes strain emm197]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment