Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT51_RS07460 Genome accession   NZ_CP035448
Coordinates   1457563..1458345 (-) Length   260 a.a.
NCBI ID   WP_038434236.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452563..1463345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS07435 (ETT51_07555) gatB 1452644..1454083 (-) 1440 WP_009880806.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  ETT51_RS07440 (ETT51_07560) gatA 1454083..1455549 (-) 1467 WP_011528911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT51_RS07445 (ETT51_07565) gatC 1455549..1455851 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT51_RS07450 (ETT51_07570) - 1456083..1456403 (-) 321 Protein_1406 putative PEP-binding protein -
  ETT51_RS07455 (ETT51_07580) - 1456862..1457416 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  ETT51_RS07460 (ETT51_07585) codY 1457563..1458345 (-) 783 WP_038434236.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT51_RS07465 (ETT51_07590) - 1458563..1459777 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  ETT51_RS07470 (ETT51_07595) - 1460008..1460460 (+) 453 WP_002992571.1 universal stress protein -
  ETT51_RS07475 (ETT51_07600) - 1460583..1461971 (-) 1389 WP_063632405.1 Cof-type HAD-IIB family hydrolase -
  ETT51_RS07480 (ETT51_07605) - 1462043..1463008 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28647.79 Da        Isoelectric Point: 4.5611

>NTDB_id=302910 ETT51_RS07460 WP_038434236.1 1457563..1458345(-) (codY) [Streptococcus pyogenes strain emm70]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPIESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=302910 ETT51_RS07460 WP_038434236.1 1457563..1458345(-) (codY) [Streptococcus pyogenes strain emm70]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTATTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

50.98

98.077

0.5