Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ETT54_RS00615 Genome accession   NZ_CP035445
Coordinates   98606..98890 (+) Length   94 a.a.
NCBI ID   WP_011284422.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm92     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93606..103890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT54_RS00590 (ETT54_00590) - 95566..95931 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT54_RS00595 (ETT54_00595) comGA 96024..96948 (+) 925 Protein_80 competence type IV pilus ATPase ComGA -
  ETT54_RS00600 (ETT54_00600) comGB 96884..97918 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT54_RS00605 (ETT54_00605) comGC 97920..98246 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT54_RS00610 (ETT54_00610) comGD 98221..98649 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  ETT54_RS00615 (ETT54_00615) comGE 98606..98890 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  ETT54_RS00620 (ETT54_00620) comGF 98883..99317 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT54_RS00625 (ETT54_00625) comGG 99301..99627 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT54_RS00630 (ETT54_00630) comGH 99725..100678 (+) 954 WP_038433850.1 class I SAM-dependent methyltransferase Machinery gene
  ETT54_RS00635 (ETT54_00635) - 100737..101933 (+) 1197 WP_111711330.1 acetate kinase -
  ETT54_RS00640 (ETT54_00640) - 102120..102419 (+) 300 Protein_89 hypothetical protein -
  ETT54_RS00645 (ETT54_00645) proC 102502..103272 (-) 771 WP_038433852.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10654.59 Da        Isoelectric Point: 8.9043

>NTDB_id=302565 ETT54_RS00615 WP_011284422.1 98606..98890(+) (comGE) [Streptococcus pyogenes strain emm92]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEITLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=302565 ETT54_RS00615 WP_011284422.1 98606..98890(+) (comGE) [Streptococcus pyogenes strain emm92]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATTGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATAACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383