Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT63_RS01980 Genome accession   NZ_CP035436
Coordinates   380906..381688 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain emm89.14     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 375906..386688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT63_RS01960 (ETT63_01960) - 376243..377208 (-) 966 WP_014407795.1 asparaginase -
  ETT63_RS01965 (ETT63_01965) - 377280..378668 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  ETT63_RS01970 (ETT63_01970) - 378791..379243 (-) 453 WP_002992571.1 universal stress protein -
  ETT63_RS01975 (ETT63_01975) - 379474..380688 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  ETT63_RS01980 (ETT63_01980) codY 380906..381688 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT63_RS01985 (ETT63_01985) - 381835..382389 (+) 555 WP_002983281.1 cysteine hydrolase family protein -
  ETT63_RS09445 (ETT63_01995) - 382848..383168 (+) 321 Protein_333 putative PEP-binding protein -
  ETT63_RS02000 (ETT63_02000) gatC 383400..383702 (+) 303 WP_136267465.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT63_RS02005 (ETT63_02005) gatA 383702..385168 (+) 1467 WP_136267467.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT63_RS02010 (ETT63_02010) gatB 385168..386607 (+) 1440 WP_063811844.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=301735 ETT63_RS01980 WP_002983278.1 380906..381688(+) (codY) [Streptococcus pyogenes strain emm89.14]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=301735 ETT63_RS01980 WP_002983278.1 380906..381688(+) (codY) [Streptococcus pyogenes strain emm89.14]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTAACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504