Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT71_RS07355 Genome accession   NZ_CP035428
Coordinates   1437281..1438063 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain emmSTG866.1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1432281..1443063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT71_RS07325 (ETT71_07320) gatB 1432362..1433801 (-) 1440 WP_002983292.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  ETT71_RS07330 (ETT71_07325) gatA 1433801..1435267 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT71_RS07335 (ETT71_07330) gatC 1435267..1435569 (-) 303 WP_136094874.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT71_RS07340 (ETT71_07335) - 1435801..1436121 (-) 321 Protein_1360 putative PEP-binding protein -
  ETT71_RS07350 (ETT71_07345) - 1436580..1437134 (-) 555 WP_002983281.1 cysteine hydrolase family protein -
  ETT71_RS07355 (ETT71_07350) codY 1437281..1438063 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT71_RS07360 (ETT71_07355) - 1438281..1439495 (-) 1215 WP_136269953.1 pyridoxal phosphate-dependent aminotransferase -
  ETT71_RS07365 (ETT71_07360) - 1439726..1440178 (+) 453 WP_002992571.1 universal stress protein -
  ETT71_RS07370 (ETT71_07365) - 1440301..1441689 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  ETT71_RS07375 (ETT71_07370) - 1441761..1442726 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=301022 ETT71_RS07355 WP_002983278.1 1437281..1438063(-) (codY) [Streptococcus pyogenes strain emmSTG866.1]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=301022 ETT71_RS07355 WP_002983278.1 1437281..1438063(-) (codY) [Streptococcus pyogenes strain emmSTG866.1]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504